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How Anesthesia Works - Yale Medicine Explains

April 22, 2025

Transcript

  • 00:05We have nerve endings
  • 00:07everywhere,
  • 00:08literally everywhere.
  • 00:10And ordinarily,
  • 00:12from these nerve endings,
  • 00:13pain gets transmitted.
  • 00:16You can kind of think
  • 00:17of them as
  • 00:18your early warning system. They
  • 00:20are the first line of
  • 00:21defense that you have against
  • 00:22threats in your environment.
  • 00:25So it could be a
  • 00:25cut. It could be an
  • 00:27incision. It could be, something
  • 00:29blunt. That initiates
  • 00:31a chemical response
  • 00:33that is transmitted to the
  • 00:34spinal cord then travel to
  • 00:36the brain and that's how
  • 00:37pain is essentially perceived.
  • 00:40Now this is in comparison
  • 00:41to chronic pain. Chronic pain
  • 00:43is essentially a
  • 00:44response. Right? So this is
  • 00:45an ongoing false alarm that
  • 00:48really does not provide you
  • 00:49or the body any benefit.
  • 00:51Pain medications and anesthetics
  • 00:54utilize
  • 00:55a very large number of
  • 00:56different mechanisms.
  • 00:57But in general, it's interrupting
  • 01:00those pathways.
  • 01:01From wherever
  • 01:02the insult or the incision
  • 01:04is or the puncture is
  • 01:05and disrupt that communication to
  • 01:07the spinal cord.
  • 01:08So that pain is ultimately
  • 01:10not experienced.
  • 01:15There are a few different
  • 01:16types of anesthesia that we
  • 01:18use now. One is a
  • 01:19local anesthetic, right, which many
  • 01:21of you have probably experienced
  • 01:22in your doctor's office or
  • 01:23your dentist office.
  • 01:25We have regional anesthetic techniques,
  • 01:27what we call monitored anesthesia
  • 01:29care which is a very
  • 01:30deep sedation
  • 01:31and then general anesthesia.
  • 01:35Regional anesthesia
  • 01:36is an anesthetic technique by
  • 01:38which we administer
  • 01:40local an aesthetic in and
  • 01:41around large nerves that provide
  • 01:44sensation to significant sections of
  • 01:46our extremities or torso.
  • 01:49Those are sometimes done on
  • 01:51nerves in the periphery
  • 01:53and sometimes they're done on
  • 01:55nerves closer to
  • 01:57the spinal cord. And that
  • 01:58doesn't mean that it's dangerous
  • 02:00because it's closer to the
  • 02:01spinal cord. It just means
  • 02:02that you're getting more nerve
  • 02:04coverage
  • 02:05the closer you get to
  • 02:06the source of the nerves.
  • 02:09So for laboring women, the
  • 02:10injection is around the low
  • 02:12back, and so it numbs
  • 02:14all the nerves from that
  • 02:15injection site and a little
  • 02:16bit above
  • 02:17down to the feet.
  • 02:21General anesthesia means that your
  • 02:23body is completely asleep. You're
  • 02:24not experiencing pain. What we
  • 02:26are doing is creating
  • 02:28a
  • 02:29space around both the brain
  • 02:31and the body which is
  • 02:32characterized
  • 02:32by unconsciousness,
  • 02:34analgesia,
  • 02:36amnesia
  • 02:36and paralysis
  • 02:38with the maintenance of physiologic
  • 02:39function.
  • 02:40And that physiologic function is
  • 02:42monitored and maintained
  • 02:44by your anesthesiologist
  • 02:45while you are as we
  • 02:46say sleeping.
  • 02:50Another type of anesthesia
  • 02:52is IV anesthesia,
  • 02:54which like general anesthesia,
  • 02:56it does afford one hypnosis
  • 02:59and level of numbness, but
  • 03:01usually you're not deep to
  • 03:03the point where you need
  • 03:04a breathing device for your
  • 03:06airway to be protected. This
  • 03:08is commonly seen
  • 03:09in cases like colonoscopies,
  • 03:11endoscopy,
  • 03:12or eye surgery.
  • 03:15Your basic physiology
  • 03:17is not only being maintained,
  • 03:19but an anesthesiologist
  • 03:21focusing on
  • 03:23you holistically
  • 03:24and helping to make sure
  • 03:26that you stay in good
  • 03:27balance.
  • 03:32One of the things that
  • 03:33we are seeing in anesthesia
  • 03:35is really a move towards
  • 03:36what we call a perioperative
  • 03:38home. Where patients are not
  • 03:40under the care of an
  • 03:41anesthesiologist
  • 03:42only during the immediate preoperative
  • 03:43and intraoperative period but really
  • 03:46becoming involved in care three
  • 03:47to six months prior to
  • 03:49a patient coming to surgery,
  • 03:50during surgery and then their
  • 03:52postoperative care afterwards.
  • 03:54And chronic pain medicine provides
  • 03:56an ability
  • 03:57to
  • 03:58attenuate risk factors for the
  • 03:59development of chronic pain after
  • 04:01surgery,
  • 04:02as well as to facilitate
  • 04:04the development
  • 04:05of comprehensive pain plans
  • 04:07to
  • 04:08minimize discomfort in the post
  • 04:10operative period both in and
  • 04:11out of the hospital.
  • 04:14It's a very exciting time
  • 04:15in anesthesia.
  • 04:17We're always
  • 04:18interrogating and really asking the
  • 04:20questions.
  • 04:21What does the data show?
  • 04:23So that we can do
  • 04:25this shared decision making with
  • 04:26our patients.
  • 04:28Anesthesiology
  • 04:29has become extraordinarily
  • 04:31safe,
  • 04:32both because of the monitoring
  • 04:34that we have, the medication
  • 04:36that we have, and the
  • 04:38vigilance
  • 04:39that we have.