2006
Mapping the Binding Site on CD8β for MHC Class I Reveals Mutants with Enhanced Binding
Devine L, Thakral D, Nag S, Dobbins J, Hodsdon ME, Kavathas PB. Mapping the Binding Site on CD8β for MHC Class I Reveals Mutants with Enhanced Binding. The Journal Of Immunology 2006, 177: 3930-3938. PMID: 16951356, DOI: 10.4049/jimmunol.177.6.3930.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBinding SitesCD8 AntigensChlorocebus aethiopsCOS CellsHistocompatibility Antigens Class IHumansMiceMolecular Sequence DataMutagenesisConceptsMHC class IClass IT cellsT cell responsesEffective immune responseT cell recognitionT cell hybridomasT cell membraneImmune responseCoreceptor functionCell responsesCell hybridomasInfected cellsCell recognitionIdentified mutationsCD8alphaCoreceptorCD8betaCDR3 loopsCellsEnhanced bindingCD8ImmunotherapyCD8alphabetaCD8β
2002
The Complementarity-Determining Region-Like Loops of CD8α Interact Differently with β2-Microglobulin of the Class I Molecules H-2Kb and Thymic Leukemia Antigen, While Similarly with Their α3 Domains
Devine L, Rogozinski L, Naidenko OV, Cheroutre H, Kavathas PB. The Complementarity-Determining Region-Like Loops of CD8α Interact Differently with β2-Microglobulin of the Class I Molecules H-2Kb and Thymic Leukemia Antigen, While Similarly with Their α3 Domains. The Journal Of Immunology 2002, 168: 3881-3886. PMID: 11937542, DOI: 10.4049/jimmunol.168.8.3881.Peer-Reviewed Original ResearchAmino Acid SequenceAmino Acid SubstitutionAnimalsAntigens, NeoplasmBeta 2-MicroglobulinCD8 AntigensComplementarity Determining RegionsCOS CellsDimerizationH-2 AntigensImmune SeraMembrane GlycoproteinsMiceMolecular Sequence DataMutagenesis, Site-DirectedPeptide FragmentsProtein BindingProtein Structure, SecondaryProtein Structure, TertiaryThymus GlandTransfection
1999
Orientation of the Ig domains of CD8 alpha beta relative to MHC class I.
Devine L, Sun J, Barr M, Kavathas P. Orientation of the Ig domains of CD8 alpha beta relative to MHC class I. The Journal Of Immunology 1999, 162: 846-51. PMID: 9916707, DOI: 10.4049/jimmunol.162.2.846.Peer-Reviewed Original Research