2008
Differential Expression of the Human CD8β Splice Variants and Regulation of the M-2 Isoform by Ubiquitination
Thakral D, Dobbins J, Devine L, Kavathas PB. Differential Expression of the Human CD8β Splice Variants and Regulation of the M-2 Isoform by Ubiquitination. The Journal Of Immunology 2008, 180: 7431-7442. PMID: 18490743, DOI: 10.4049/jimmunol.180.11.7431.Peer-Reviewed Original ResearchConceptsCytoplasmic tailSplice variantsExpression patternsCell surfaceDifferent cytoplasmic tailsGene splice variantsMRNA expression patternsMRNA levelsFluorescent chimerasHuman genesHuman lineageDifferential mRNA expression patternsHeterodimer functionsExtracellular domainLysine residuesQuantitative RT-PCRDifferential expressionLysosomal compartmentTCR complexFunctional significanceIsoformsCD8B geneUbiquitinationCell linesPrimary human
1996
Lymphocyte Migration across the Anterior and Posterior Blood–Retinal Barrierin Vitro
Devine L, Lightman S, Greenwood J. Lymphocyte Migration across the Anterior and Posterior Blood–Retinal Barrierin Vitro. Cellular Immunology 1996, 168: 267-275. PMID: 8640874, DOI: 10.1006/cimm.1996.0075.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigensArrestinBlood-Retinal BarrierCell AdhesionCell LineChemotaxis, LeukocyteEndothelium, VascularEye ProteinsInterferon-gammaInterleukin-1Lymph NodesLymphocyte ActivationLymphocyte SubsetsMuromonab-CD3OvalbuminPigment Epithelium of EyeRatsRats, Inbred LewRats, Inbred StrainsReceptor-CD3 Complex, Antigen, T-CellRecombinant ProteinsRetinal VesselsSpecific Pathogen-Free OrganismsT-Lymphocytes, Helper-InducerTuberculinConceptsAntigen-specific T cell linesRat retinal pigment epitheliumBlood-retinal barrierT cell linesPLN cellsEndothelial cellsLymphocyte migrationPeripheral lymph node cellsCell linesRetinal vascular endotheliumLymph node cellsCross-linking CD3Migration of lymphocytesRetinal endothelial cellsRetinal pigment epitheliumCombination of CD3PVG ratsRetinal endotheliumIFN-gamma activationLewis ratsNode cellsS-antigenICAM-1IFN-gammaPigment epithelium