Featured Publications
Alcohol Use Disorder and Chronic Pain: An Overlooked Epidemic
De Aquino J, Sloan M, Nunes J, Costa G, Katz J, de Oliveira D, Ra J, Tang V, Petrakis I. Alcohol Use Disorder and Chronic Pain: An Overlooked Epidemic. American Journal Of Psychiatry 2024, 181: 391-402. PMID: 38706339, PMCID: PMC11521207, DOI: 10.1176/appi.ajp.20230886.Peer-Reviewed Original ResearchConceptsAlcohol use disorderChronic painAUD studiesChronic pain disordersChronic pain outcomesRisk of relapseAlcohol withdrawal syndromeAssessment of painHigher levels of alcohol consumptionLevels of alcohol consumptionWithdrawal syndromePain disordersPain outcomesAcute toleranceNeurobiological changesClinical significanceUse disorderPainClinical relevanceSelf-reportAlcohol intoxicationAlcohol consumptionGeneral populationMedical conditionsNarrative review
2022
Pharmacological Treatments for Cocaine Craving: What Is the Way Forward? A Systematic Review
Lassi D, Malbergier A, Negrão A, Florio L, De Aquino J, Castaldelli-Maia J. Pharmacological Treatments for Cocaine Craving: What Is the Way Forward? A Systematic Review. Brain Sciences 2022, 12: 1546. PMID: 36421870, PMCID: PMC9688748, DOI: 10.3390/brainsci12111546.Peer-Reviewed Original ResearchCocaine use disorderCocaine cravingUse disorderMeta-chlorophenylpiperazineShort-term treatmentAnti-craving effectsAlcohol use disorderAttention deficit hyperactivityEfficacy of pharmacotherapyCraving assessmentCraving measuresBipolar disorderRelapse preventionDrop-out ratePromote abstinenceCocaine useCravingTreatment-seekingCocaineNon-pharmacological treatmentInvestigational pharmacotherapyLong-term treatmentAbstinencePharmacological treatmentClinical trialsBrain Correlates of the Alcohol Use Disorder Pharmacotherapy Response: A Systematic Review of Neuroimaging Studies
Florence L, Lassi D, Kortas G, Lima D, de Azevedo-Marques Périco C, Andrade A, Torales J, Ventriglio A, De Berardis D, De Aquino J, Castaldelli-Maia J. Brain Correlates of the Alcohol Use Disorder Pharmacotherapy Response: A Systematic Review of Neuroimaging Studies. Brain Sciences 2022, 12: 386. PMID: 35326342, PMCID: PMC8946664, DOI: 10.3390/brainsci12030386.Peer-Reviewed Original ResearchAlcohol use disorderFunctional magnetic resonance imagingPharmacotherapy responseBrain regionsReward systemSystematic review of neuroimaging studiesFactors of alcohol use disorderReview of neuroimaging studiesPositron emission tomographyBrain reward systemAnterior cingulate cortexDorsolateral prefrontal cortexNegative affective statesEffects of pharmacotherapySingle-photon emission computed tomographyProton magnetic resonance spectroscopyAlcohol use statusNeuroadaptive changesDopamine systemPrefrontal cortexBrain correlatesCingulate cortexLimbic regionsAddictive behaviorsNeuroimaging studies