O-294 Human oocyte survival, early embryo development, metabolic fingerprinting, and pregnancy outcomes following ultra-rapid or standard vitrification and thawing
Aydin B, Hudkova D, Maggiotto G, Kal N, Osmanllari U, Unsal E, Baltaci V, Aktuna S, Yonar D, Dorofeyeva U, Kotliarova E, Vitushynska M, Misyura Y, Yetim I, Babarikova V. O-294 Human oocyte survival, early embryo development, metabolic fingerprinting, and pregnancy outcomes following ultra-rapid or standard vitrification and thawing. Human Reproduction 2024, 39: deae108.351. DOI: 10.1093/humrep/deae108.351.Peer-Reviewed Original ResearchUltra-rapid vitrificationPregnancy outcomesVitrification-thawingNo significant differenceDay 1Non-invasive biomarkersOocyte survivalEmbryo competenceEmbryo transferOocyte viabilitySignificant differenceMetabolic profileDay 6Embryo culture fluidVitrification protocolIntracytoplasmic sperm injectionClinical pregnancy rateFavorable pregnancy outcomesMetabolic fingerprintsAssessed 5 daysEnhance pregnancy outcomeEmbryo developmentMann-Whitney U testSecretome profileUltra-rapidO-272 Preimplantation genetic testing of the first polar body is useful for predicting embryo euploidy: data from 1,836 donor oocytes
Maggiotto G, Aydin B, Strelko H, Hudkova D, Unsal E, Kal N, Yetim I, Misyura Y, Kotliarova E, Vitushynska M, Dorofeyeva U. O-272 Preimplantation genetic testing of the first polar body is useful for predicting embryo euploidy: data from 1,836 donor oocytes. Human Reproduction 2024, 39: deae108.319. DOI: 10.1093/humrep/deae108.319.Peer-Reviewed Original ResearchPreimplantation genetic testingDonor oocytesEuploid oocytesEuploid embryosChromosomal statusGenetic testingEmbryo euploidyEuploidy ratePGT-ABlastocyst euploidy ratesEmbryo chromosomal statusFresh donor oocytesPGT-A analysisDonor oocyte cyclesIn vitro maturationPolar body biopsyPoor reproductive outcomesMann-Whitney U testAge groupsHours post-hCGEuploidy statusGenerate blastocystsOocyte cyclesOocyte survivalBody biopsy