2024
O-272 Preimplantation genetic testing of the first polar body is useful for predicting embryo euploidy: data from 1,836 donor oocytes
Maggiotto G, Aydin B, Strelko H, Hudkova D, Unsal E, Kal N, Yetim I, Misyura Y, Kotliarova E, Vitushynska M, Dorofeyeva U. O-272 Preimplantation genetic testing of the first polar body is useful for predicting embryo euploidy: data from 1,836 donor oocytes. Human Reproduction 2024, 39: deae108.319. DOI: 10.1093/humrep/deae108.319.Peer-Reviewed Original ResearchPreimplantation genetic testingDonor oocytesEuploid oocytesEuploid embryosChromosomal statusGenetic testingEmbryo euploidyEuploidy ratePGT-ABlastocyst euploidy ratesEmbryo chromosomal statusFresh donor oocytesPGT-A analysisDonor oocyte cyclesIn vitro maturationPolar body biopsyPoor reproductive outcomesMann-Whitney U testAge groupsHours post-hCGEuploidy statusGenerate blastocystsOocyte cyclesOocyte survivalBody biopsy
2006
Relationship between embryo quality and aneuploidies
Baltaci V, Satiroglu H, Kabukçu C, Ünsal E, Aydinuraz B, Üner Ö, Aktas Y, Çetinkaya E, Turhan F, Aktan A. Relationship between embryo quality and aneuploidies. Reproductive BioMedicine Online 2006, 12: 77-82. PMID: 16454940, DOI: 10.1016/s1472-6483(10)60984-4.Peer-Reviewed Original ResearchConceptsEmbryo qualityGrade IGrade IIPreimplantation genetic diagnosisGrade I.High-grade embryosBetter developmental potentialEmbryo gradeEmbryo transferChromosomal abnormalitiesAneuploid embryosChromosomal statusMorphological gradePGD procedureMorphological evaluationGenetic diagnosisPGD resultsPolyploid embryosAbnormal embryosHigher proportionSitu hybridizationAneuploidyNormal embryosDevelopmental potentialGenetic status