Erica Spatz, MD, MHS
Associate Professor of Cardiology and Associate Professor of Epidemiology (Chronic Diseases)Cards
About
Research
Publications
2024
Embracing Change Human-Centered Cardiovascular Medicine in the Era of AI
You S, Yao X, Bikdeli B, Spatz E. Embracing Change Human-Centered Cardiovascular Medicine in the Era of AI. Journal Of The American College Of Cardiology 2024, 84: 1495-1497. PMID: 39357943, DOI: 10.1016/j.jacc.2024.08.047.Peer-Reviewed Original ResearchDiagnostic Yield and Clinical Utility of Coronary Angiography Versus Coronary Function Testing in Women With Angina and Nonobstructive Coronary Arteries.
Cigarroa N, Latif N, Maayah M, Khokhar A, Kunnirickal S, Schwann A, Maciejewski K, Odanovic N, Mazure C, Spatz E, Pfau S, Lansky A, Shah S. Diagnostic Yield and Clinical Utility of Coronary Angiography Versus Coronary Function Testing in Women With Angina and Nonobstructive Coronary Arteries. Journal Of The American Heart Association 2024, 13: e035852. PMID: 39291500, DOI: 10.1161/jaha.124.035852.Peer-Reviewed Original ResearchCoronary function testingNonobstructive coronary arteriesInvasive coronary angiographyCoronary microvascular dysfunctionCoronary angiographyVasomotor disordersFunction testsCoronary arteryAntianginal therapyDiagnostic yieldVasospastic anginaMicrovascular dysfunctionDiagnostic yield of invasive coronary angiographyNonobstructive coronary artery diseaseSuspected ischemic heart diseaseCalcium channel blockersCoronary vasomotor disordersSymptomatic myocardial bridgingCoronary artery diseaseIschemic heart diseaseChannel blockersAnatomic diagnosisEndothelial dysfunctionArtery diseaseMyocardial bridgingRace, Ethnicity, and Gender Differences in Patient Reported Well-Being and Cognitive Functioning Within 3 Months of Symptomatic Illness During COVID-19 Pandemic
Hill M, Huebinger R, Ebna Mannan I, Yu H, Wisk L, O’Laughlin K, Gentile N, Stephens K, Gottlieb M, Weinstein R, Koo K, Santangelo M, Saydah S, Spatz E, Lin Z, Schaeffer K, Kean E, Montoy J, Rodriguez R, Idris A, McDonald S, Elmore J, Venkatesh A. Race, Ethnicity, and Gender Differences in Patient Reported Well-Being and Cognitive Functioning Within 3 Months of Symptomatic Illness During COVID-19 Pandemic. Journal Of Racial And Ethnic Health Disparities 2024, 1-18. PMID: 39172356, DOI: 10.1007/s40615-024-02124-8.Peer-Reviewed Original ResearchPROMIS T-scoresPain interferenceBlack participantsWell-beingHealth-related quality of lifeNon-Hispanic white participantsCognitive functionMeasures of healthHealth-related qualityMethodsThis prospective cohort studyFollow-up surveyProspective cohort studyT-scoreQuality of lifeCOVID-19-related health outcomesLower well-beingPROMIS-29Physical functionHealth outcomesBaseline to 3Social participationWhite participantsCohort studyCOVID-19Sleep disturbanceFloods and cause-specific mortality in the United States during 2001-2020
Chu L, Warren J, Spatz E, Lowe S, Lu Y, Ma X, Ross J, Krumholz H, Chen K. Floods and cause-specific mortality in the United States during 2001-2020. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1705.Peer-Reviewed Original ResearchThe association between prolonged SARS-CoV-2 symptoms and work outcomes
Venkatesh A, Yu H, Malicki C, Gottlieb M, Elmore J, Hill M, Idris A, Montoy J, O’Laughlin K, Rising K, Stephens K, Spatz E, Weinstein R, Group F. The association between prolonged SARS-CoV-2 symptoms and work outcomes. PLOS ONE 2024, 19: e0300947. PMID: 39074096, PMCID: PMC11285965, DOI: 10.1371/journal.pone.0300947.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 symptomsReturn to workAssociated with increased oddsAnalyzed self-reported dataNational cohort studySelf-reported dataLong COVIDCOVID-19 pandemicLost work timePublic health emergencyWork absenteeismMissed workdaysElectronic surveyEmployment statusSARS-CoV-2 infectionWell-being impactsOdds ratioWork lossCohort studyNumerous healthImpact of long COVIDCOVID-19Risk factorsThree-monthsHealth emergencyTransforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.
Shimbo D, Shah R, Abdalla M, Agarwal R, Ahmad F, Anaya G, Attia Z, Bull S, Chang A, Commodore-Mensah Y, Ferdinand K, Kawamoto K, Khera R, Leopold J, Luo J, Makhni S, Mortazavi B, Oh Y, Savage L, Spatz E, Stergiou G, Turakhia M, Whelton P, Yancy C, Iturriaga E. Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report. Hypertension 2024 PMID: 39011653, DOI: 10.1161/hypertensionaha.124.22095.Peer-Reviewed Original ResearchMachine learning toolsManagement of hypertensionNational HeartArtificial intelligenceBlood InstitutePredictive of incident hypertensionHealth care systemImplementation challengesDiverse group of stakeholdersAI toolsPopulation healthMeasurement of blood pressureCare systemHealth careIncident hypertensionHypertension riskEra of artificial intelligenceHypertension diagnosisLearning toolsManaging hypertensionHypertension-related complicationsAntihypertensive medicationsHealthPublic healthGroups of stakeholdersEvaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA)
Maayah M, Latif N, Vijay A, Gallegos C, Cigarroa N, Martinez E, Mazure C, Miller E, Spatz E, Shah S. Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA). Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 3: 102195. PMID: 39166160, PMCID: PMC11330936, DOI: 10.1016/j.jscai.2024.102195.Peer-Reviewed Original ResearchIschemic heart diseaseNonobstructive coronary arteriesCoronary artery diseaseArtery diseaseObstructive coronary artery diseaseCoronary arteryLong-term cardiovascular prognosisHeart diseaseSuspected ischemic heart diseaseAtherosclerotic coronary artery diseaseCoronary vasomotor disordersPretest probability of diseasePragmatic diagnostic algorithmExpert consensus documentEvaluating ischemic heart diseaseImpact quality of lifeQuality of lifeSymptomatic patientsPretest probabilityANOCACardiovascular prognosisVasomotor disordersDiagnostic evaluationPersistent symptomsDiagnostic strategiesComparing Methods for Identifying Post-Market Patient Preferences at the Point of Decision-Making: Insights from Patients with Chronic Pain Considering a Spinal Cord Stimulator Device
Golembiewski E, Leon-Garcia M, Gravholt D, Brito J, Spatz E, Bendel M, Montori V, Maraboto A, Hartasanchez S, Hargraves I. Comparing Methods for Identifying Post-Market Patient Preferences at the Point of Decision-Making: Insights from Patients with Chronic Pain Considering a Spinal Cord Stimulator Device. Patient Preference And Adherence 2024, 18: 1325-1344. PMID: 38953019, PMCID: PMC11215661, DOI: 10.2147/ppa.s431378.Peer-Reviewed Original ResearchSpinal cord stimulation devicesPatient preferencesPain clinicChronic painVideo coding schemePatientsStimulation deviceIdentifying patient preferencesPost-encounter interviewsPost-encounter surveysCoding schemePatient-clinician encountersPatient surveyPost-marketingPatient encountersVideoSets of utterancesPotential preferencesData setsPatient's situationDevelopment and multinational validation of an algorithmic strategy for high Lp(a) screening
Aminorroaya A, Dhingra L, Oikonomou E, Saadatagah S, Thangaraj P, Vasisht Shankar S, Spatz E, Khera R. Development and multinational validation of an algorithmic strategy for high Lp(a) screening. Nature Cardiovascular Research 2024, 3: 558-566. PMID: 39195936, DOI: 10.1038/s44161-024-00469-1.Peer-Reviewed Original ResearchElectronic health recordsAssociated with premature atherosclerotic cardiovascular diseaseElevated Lp(aHealth recordsUK BiobankPremature atherosclerotic cardiovascular diseaseMachine learning modelsAtherosclerotic cardiovascular diseaseCohort studyReal-world settingsTargeted screeningCardiovascular diseaseLearning modelsNovel targeted therapeuticsAlgorithmic strategiesCohortProbability thresholdScreeningClinical featuresValidation cohortElevated lipoproteinRisk inspectionARICLp(aUtilization of Fixed-Dose Combination Treatment for Hypertension in Medicare and Medicaid From 2016 to 2020
Essa M, Ross J, Dhruva S, Desai N, Spatz E, Faridi K. Utilization of Fixed-Dose Combination Treatment for Hypertension in Medicare and Medicaid From 2016 to 2020. Circulation Cardiovascular Quality And Outcomes 2024, 17: e010697. PMID: 38712553, DOI: 10.1161/circoutcomes.123.010697.Peer-Reviewed Original Research
Clinical Care
Overview
Erica Spatz, MD, MHS, is a general cardiologist who treats a variety of conditions that relate to the heart and circulatory system. In addition to emphasizing prevention to her patients, she is an active researcher who investigates ways to prevent heart attacks and strokes, so that more people can live long and healthy lives.
“The field of prevention is exciting. We are rapidly developing new ways of estimating people’s risk of future heart disease, and we have new medications and tools to reduce that risk,” says Dr. Spatz, who is especially interested in applying “precision medicine” to prevention. This is making conversations with patients in her practice more specific and less generic. “I am thinking, ‘What are the patient’s risk factors? What's unique about their biology, their genetics, and their biography? What are the aspects of their lives that may be contributing to cardiovascular risk or, on the contrary, promoting cardiovascular health? What might be the best strategies for reducing risk and improving their health outcomes?’ The onus is on us as clinicians, physicians, nurses, and pharmacists, to really understand the person before us.”
We need to be working at multiple levels to reduce heart disease, Spatz says. “We need strong policies and coordinated community efforts to promote healthier lifestyles and overall well-being. There is so much we can be doing to make ‘healthy’ the easy choice for our population. At the individual level, there is an opportunity to better capture the personalized biological factors, experiences, and behaviors that inform cardiovascular risk—through digital technology and surveys.”
Lifestyle changes are often considered the bedrock of preventing heart disease, and while this can be difficult for some people—especially if they are overwhelmed with other life challenges—small achievable goals go a long way, Dr. Spatz says. “I try to think about this from a lifelong perspective. Cardiovascular disease prevention is hard work and people can't be perfect all the time, so I try to find specific things people can work on as well as opportunities when this makes sense in a person's life. If I can help them to define a healthier path, then I think the ripple effects can be massive.”
In addition to caring for patients, Dr. Spatz serves as a clinical investigator for the Center for Outcomes Research & Evaluation (CORE), an organization at Yale School of Medicine that focuses on health care quality, where she researches individualized approaches to preventing and managing cardiovascular disease, health disparities across the health care system, and ways to engage patients as partners in their care. She also is a cofounder of Project Access-New Haven—a network of physicians, hospitals, and community organizations partnering to provide donated specialty care to underserved patients in New Haven.
Clinical Specialties
Fact Sheets
Heart Attack (Myocardial Infarction)
Learn More on Yale MedicineHeart Disease in Women
Learn More on Yale MedicineCoronary Artery Disease (CAD)
Learn More on Yale MedicineChest Pain
Learn More on Yale Medicine
Yale Medicine News
News & Links
News
- December 09, 2024
YSPH community supports local agencies with gift basket raffle
- November 18, 2024
Implementing eConsult Program Strategies Highlighted in PLOS One
- November 05, 2024
Yale Researchers at American Heart Association Scientific Session 2024
- October 24, 2024
New Analytics Center for Cardiovascular Medicine