Carolyn M. Mazure, PhD
Norma Weinberg Spungen and Joan Lebson Bildner Professor in Women's Health Research and Professor of Psychiatry and of PsychologyCards
Additional Titles
Director, Women's Health Research at Yale, Yale Medical School
Appointments
Contact Info
Additional Titles
Director, Women's Health Research at Yale, Yale Medical School
Appointments
Contact Info
Additional Titles
Director, Women's Health Research at Yale, Yale Medical School
Appointments
Contact Info
About
Titles
Norma Weinberg Spungen and Joan Lebson Bildner Professor in Women's Health Research and Professor of Psychiatry and of Psychology
Director, Women's Health Research at Yale, Yale Medical School
Biography
Carolyn M. Mazure is the Norma Weinberg Spungen and Joan Lebson Bildner Professor in Women’s Health Research, and Professor of Psychiatry and Psychology. After three years at the National Institutes of Health and fellowship training at Yale, Dr. Mazure joined the Yale faculty — becoming an active clinician and NIH-funded researcher. She was the Director of Psychiatry’s Adult Inpatient Program at Yale-New Haven Hospital, and has held a variety of other leadership roles, including Associate Dean for Faculty at Yale School of Medicine, Scientific Director of NIH-funded SCOR(E) interdisciplinary research grants, and PI of NIH-funded junior faculty training grants.
She created Women’s Health Research at Yale, the university’s interdisciplinary research center on the health of women and the interplay of sex, gender, and health. The center studies a wide breadth of topics from cardiovascular disease to cancers. Since its inception in 1998, the center has been recognized as a national model for launching research, translating findings, sharing health information with the public and policymakers, and providing mentored training in interdisciplinary team science.
In 2023, Dr. Mazure was appointed Chair of the White House Initiative on Women's Health Research, which aims to fundamentally change how the nation approaches and funds women's health research.
Her research contributions have focused on depression, the single greatest cause of disability for women in the U.S. and globally, including the sex-and-gender-specific relationship of stress to depression and co-occurring addictive behaviors (such as smoking, and opioid use and misuse). Current research targets the intersection of biological and social factors affecting the health of women, gender-specific strategies for promoting resilience, and health policies that serve to advance economic stability for women.
Dr. Mazure has served on the Advisory Committee for the NIH Office for Research on Women’s Health, provided testimony to the U.S. Congress on the health of women, served on the planning committee for the First White House Conference on Mental Health, and was a fellow for the U.S. Congress’ Committee on Oversight and Government Reform.
She has been an invited speaker at diverse venues, such as NASA, the Smithsonian Institution, and the Sorbonne, and has been a featured expert on ABC’s “Prime Time Live” and in the BBC documentary “The Science of Stress.” Her edited books include “Does Stress Cause Psychiatric Illness?” and “Understanding Depression in Women: Applying Empirical Research to Practice and Policy.”
Her national honors include the Marion Spencer Fay Award from the Institute for Women’s Health and Leadership, the American Psychological Association Distinguished Leadership Award from the Committee on Women in Psychology, the Elizabeth Blackwell Award from the National Organization for Women, and a U.S. Public Health Fellowship. Additional honors include Yale’s Stephen Fleck Clinician and Teacher Award and the Sidney J. Blatt Award for Excellence in Clinical Care, Teaching, and Research.
Appointments
Psychiatry
ProfessorPrimaryDepartment of Psychology
ProfessorSecondary
Other Departments & Organizations
- Department of Psychology
- Division of Women's Behavioral Health Research
- MORE
- Neuroscience Research Training Program (NRTP)
- Psychiatry
- Psychology Section
- Status of Women in Medicine Committee (SWIM)
- Women's Health Research at Yale
- Yale Medicine
- Yale Translational Center to Develop Gender-Sensitive Treatment for Tobacco Dependence
- Yale Ventures
Education & Training
- Post Doctoral
- Yale University Health Services (1982)
- Fellow
- Yale School of Medicine (1981)
- PhD
- Pennsylvania State University (1980)
Research
Overview
Medical Research Interests
ORCID
0000-0003-0150-5679
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Sherry McKee, PhD
Rani Hoff, MPH, PhD
Chiang-Shan Ray Li, MD, PhD
Marina Picciotto, PhD
Andrea Weinberger, PhD
Hilary Blumberg, MD
Depressive Disorder
Stress, Psychological
Women's Health
Behavior, Addictive
Psychiatry
Publications
2024
The White House Initiative on Women’s Health Research
Mazure C. The White House Initiative on Women’s Health Research. JAMA Internal Medicine 2024, 184: 1277-1278. PMID: 39348106, DOI: 10.1001/jamainternmed.2024.3592.Peer-Reviewed Original ResearchMindfulness-based therapy for insomnia in Black women: a pilot randomized controlled trial
Nam S, Jeon S, Ordway M, Mazure C, Sinha R, Yau L, Iennaco J. Mindfulness-based therapy for insomnia in Black women: a pilot randomized controlled trial. Journal Of Behavioral Medicine 2024, 47: 1094-1106. PMID: 39306634, DOI: 10.1007/s10865-024-00521-2.Peer-Reviewed Original ResearchCitationsConceptsPatient Health Questionnaire-9Spielberger State-Trait Anxiety InventoryInsomnia Severity IndexHealth educationMindfulness-based therapyBlack womenDepressive symptomsEfficacy of mindfulness-based therapyAttention control groupSleep health disparitiesPost-intervention changesState-Trait Anxiety InventoryPittsburgh Sleep Quality IndexInsomnia severity scoresSleep Quality IndexInsomnia Severity Index scoreBehavioral sleep strategiesRandomized controlled trialsClinically significant improvementPhysical activityHealth disparitiesHealthy eatingSleep hygiene practicesImprove anxietyWeekly sessionsDiagnostic Yield and Clinical Utility of Coronary Angiography Versus Coronary Function Testing in Women With Angina and Nonobstructive Coronary Arteries.
Cigarroa N, Latif N, Maayah M, Khokhar A, Kunnirickal S, Schwann A, Maciejewski K, Odanovic N, Mazure C, Spatz E, Pfau S, Lansky A, Shah S. Diagnostic Yield and Clinical Utility of Coronary Angiography Versus Coronary Function Testing in Women With Angina and Nonobstructive Coronary Arteries. Journal Of The American Heart Association 2024, 13: e035852. PMID: 39291500, DOI: 10.1161/jaha.124.035852.Peer-Reviewed Original ResearchAltmetricConceptsCoronary function testingNonobstructive coronary arteriesInvasive coronary angiographyCoronary microvascular dysfunctionCoronary angiographyVasomotor disordersFunction testsCoronary arteryAntianginal therapyDiagnostic yieldVasospastic anginaMicrovascular dysfunctionDiagnostic yield of invasive coronary angiographyNonobstructive coronary artery diseaseSuspected ischemic heart diseaseCalcium channel blockersCoronary vasomotor disordersSymptomatic myocardial bridgingCoronary artery diseaseIschemic heart diseaseChannel blockersAnatomic diagnosisEndothelial dysfunctionArtery diseaseMyocardial bridgingEvaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA)
Maayah M, Latif N, Vijay A, Gallegos C, Cigarroa N, Martinez E, Mazure C, Miller E, Spatz E, Shah S. Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA). Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 3: 102195. PMID: 39166160, PMCID: PMC11330936, DOI: 10.1016/j.jscai.2024.102195.Peer-Reviewed Original ResearchAltmetricConceptsIschemic heart diseaseNonobstructive coronary arteriesCoronary artery diseaseArtery diseaseObstructive coronary artery diseaseCoronary arteryLong-term cardiovascular prognosisHeart diseaseSuspected ischemic heart diseaseAtherosclerotic coronary artery diseaseCoronary vasomotor disordersPretest probability of diseasePragmatic diagnostic algorithmExpert consensus documentEvaluating ischemic heart diseaseImpact quality of lifeQuality of lifeSymptomatic patientsPretest probabilityANOCACardiovascular prognosisVasomotor disordersDiagnostic evaluationPersistent symptomsDiagnostic strategiesAssociations of Posttraumatic Stress Disorder Symptom Clusters and Pain Interference in Post-9/11 Veterans: Exploring Sleep Impairment and Physical Activity as Underlying Mechanisms
Emrich M, Gnall K, Garnsey C, George J, Park C, Mazure C, Hoff R. Associations of Posttraumatic Stress Disorder Symptom Clusters and Pain Interference in Post-9/11 Veterans: Exploring Sleep Impairment and Physical Activity as Underlying Mechanisms. International Journal Of Behavioral Medicine 2024, 1-14. PMID: 38438749, DOI: 10.1007/s12529-024-10268-4.Peer-Reviewed Original ResearchAltmetricConceptsPost-9/11 veteransPain interferencePhysical activityPTSD symptomsAssociated with pain interferenceModifiable health factorsSleep impairmentSymptom clustersPosttraumatic stress disorder symptom clustersWorsening pain interferencePTSD symptom clustersRe-experiencing symptomsBackgroundPosttraumatic stress disorderHealth factorsSecondary analysisTargeting sleepMethodsThe present studyVeteransHyperarousal symptomsRe-experiencingStress disorderStudy variablesPTSDPainAssociated with changesPhysical activity, posttraumatic stress, and gender: A longitudinal study of post-9/11 veterans
Gnall K, Sacco S, Sinnott S, Park C, Mazure C, Hoff R. Physical activity, posttraumatic stress, and gender: A longitudinal study of post-9/11 veterans. Journal Of Health Psychology 2024, 29: 1576-1589. PMID: 38400566, DOI: 10.1177/13591053241233380.Peer-Reviewed Original ResearchConceptsPost-9/11 veteransLeisure-time PAPhysical activityPosttraumatic stress symptomsPA engagementMilitary dischargeSelf-report questionnairesHealth habitsMental healthSecondary analysisStudy baselineLongitudinal relationshipPosttraumatic stressStress symptomsVeteransLongitudinal studyHealthObservational investigationPost-9/11GenderBaselineEngagementQuestionnaireInterventionParticipants
2023
Stress as a Risk Factor for Mental Disorders in a Gendered Environment
Mazure C, Husky M, Pietrzak R. Stress as a Risk Factor for Mental Disorders in a Gendered Environment. JAMA Psychiatry 2023, 80: 1087-1088. PMID: 37672277, DOI: 10.1001/jamapsychiatry.2023.3138.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConsiderations of Sex and Gender in FDA Tobacco Regulation
Davis D, Krishnan-Sarin S, Mazure C. Considerations of Sex and Gender in FDA Tobacco Regulation. JAMA 2023, 329: 2017-2018. PMID: 37233997, PMCID: PMC11094658, DOI: 10.1001/jama.2023.6803.Peer-Reviewed Original ResearchCitationsAltmetricThe value of teaching the influence of sex and gender on health outcomes
Martin K, Marshall A, Mazure C. The value of teaching the influence of sex and gender on health outcomes. The Lancet Haematology 2023, 10: e318-e319. PMID: 37142343, PMCID: PMC10154001, DOI: 10.1016/s2352-3026(23)00055-8.Peer-Reviewed Original ResearchAltmetricPre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers
Hennein R, Lowe S, Feingold J, Feder A, Peccoralo L, Ripp J, Mazure C, Pietrzak R. Pre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers. Journal Of Psychiatric Research 2023, 162: 88-94. PMID: 37105023, DOI: 10.1016/j.jpsychires.2023.04.009.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMajor depressive disorderPosttraumatic stress disorderProspective cohort studyHealthcare providersCohort studyLarge tertiary care hospitalPsychological sequelaeSymptoms of MDDMental health risk factorsTertiary care hospitalProbable major depressive disorderWomen's healthcare providersHealth risk factorsFrontline healthcare providersCare hospitalRisk factorsDepressive disorderGender differencesStress disorderAnxiety disordersWomenSequelaeCOVID-19DisordersCOVID-19 pandemic
Academic Achievements & Community Involvement
honor Elga R. Wasserman Courage, Clarity, and Leadership Award
Yale University AwardWomen Faculty ForumDetails09/19/2024activity Defining Sex and Gender
Oral PresentationInvited Speaker, National Academy of Medicine Annual MeetingDetails10/09/2023 - PresentWashington, DCSponsored by National Academy of Medicineactivity How to Incorporate Sex as a Biological Variable in Your Research
OtherKeynote Speaker, Emory Specialized Center of Research Excellence on Sex Differences (Emory SCORE)Details12/07/2022 - 12/07/2022Atlanta, GAactivity Frank P. Soldo III Lecture in Psychiatry Grand Rounds
LectureMassachusetts General Hospital, Harvard Medical SchoolDetails04/08/2021 - 04/08/2021Boston, MAactivity Women, Opioids and Addiction
OtherInvited Speaker, Dartmouth Hitchcock HospitalDetails02/09/2021 - 02/09/2021Lebanon, NH
News & Links
News
- October 24, 2024
Carolyn M. Mazure Receives Elga R. Wasserman Award
- October 24, 2024
Women’s Health Research at Yale Welcomes Undergraduate Fellows
- October 07, 2024Source: JAMA Internal Medicine
Carolyn M. Mazure, PhD, Viewpoint Published in JAMA Internal Medicine
- July 23, 2024
Advancements in Women’s Health Research
Related Links