Gauri Panse, MD
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Research
Publications
2025
Epithelioid Fibrous Histiocytoma With Abundant Multinucleated Giant Cells: Report of 3 Cases of an Unusual Variant With Predilection for Acral Sites
Wang S, Zubek A, Panse G. Epithelioid Fibrous Histiocytoma With Abundant Multinucleated Giant Cells: Report of 3 Cases of an Unusual Variant With Predilection for Acral Sites. American Journal Of Dermatopathology 2025, 47: 909-916. PMID: 41263920, DOI: 10.1097/dad.0000000000002937.Peer-Reviewed Original ResearchConceptsEpithelioid fibrous histiocytomaAnaplastic lymphoma kinaseMultinucleated giant cellsFibrous histiocytomaHistopathological spectrumGiant cellsAcral sitesAnaplastic lymphoma kinase positivityPresence of ALK rearrangementCases of epithelioid fibrous histiocytomaClinical follow-upBenign cutaneous neoplasmsWell-circumscribed lesionAbundant eosinophilic cytoplasmBenign fibrous histiocytomaAbundant multinucleated giant cellsSheets of epithelioid cellsYears of ageALK rearrangementEpithelioid neoplasmNo recurrenceCase seriesCutaneous neoplasmsEosinophilic cytoplasmFibrous stromaCutaneous Extracavitary Primary Effusion Lymphoma: A Case Report and Review of Literature
Dileep A, Zaki T, Leasure A, Xu M, Nelson C, Panse G. Cutaneous Extracavitary Primary Effusion Lymphoma: A Case Report and Review of Literature. Journal Of Cutaneous Pathology 2025 PMID: 41218762, DOI: 10.1111/cup.70007.Peer-Reviewed Original ResearchExtracavitary primary effusion lymphomaPrimary effusion lymphomaHuman herpesvirus 8Primary cutaneous manifestationBody cavity effusionsHistopathological featuresUnusual caseCavity effusionsElevated EBV viral loadsEBV viral loadB-cell lymphomaHistory of feverPleomorphic lymphoid cellsUnusual immunophenotypeImmunocompromised patientsAtypical cellsProgressive dyspneaCD138+CD3+CD45+Viral loadISH positivityDiagnostic pitfallsCase reportLymphoid cells325 Spatial Transcriptomics Reveals Immune Cell Subsets and Tumor-Specific Keratinocytes Associated with Premalignant Lesions in Vulvar Lichen Sclerosus
Suresh A, Abi-Raad R, Panse G, Little A. 325 Spatial Transcriptomics Reveals Immune Cell Subsets and Tumor-Specific Keratinocytes Associated with Premalignant Lesions in Vulvar Lichen Sclerosus. Journal Of Investigative Dermatology 2025, 145: e82. DOI: 10.1016/j.jid.2025.09.327.Peer-Reviewed Original ResearchIsolated perineal plaque as the initial presentation of pemphigus vulgaris
Workineh A, Panse G, Tomayko M, Little A. Isolated perineal plaque as the initial presentation of pemphigus vulgaris. JAAD Case Reports 2025, 67: 158-161. PMID: 41446696, PMCID: PMC12723278, DOI: 10.1016/j.jdcr.2025.10.034.Peer-Reviewed Original ResearchHybrid granular cell tumor/perineurioma: a report of two rare cases with PIK3CA mutations
Toklu A, Panse G, Jour G, Linos K, Cloutier J, Dehner C. Hybrid granular cell tumor/perineurioma: a report of two rare cases with PIK3CA mutations. Virchows Archiv 2025, 487: 597-604. PMID: 40159563, DOI: 10.1007/s00428-025-04089-3.Peer-Reviewed Original ResearchPeripheral nerve sheath tumorsHybrid peripheral nerve sheath tumorsRare mesenchymal neoplasmNerve sheath tumorsWell-circumscribed lesionGLUT1 stainingPIK3CA mutationsUnusual neoplasmsSheath tumorsMesenchymal neoplasmsRare caseDual differentiationDifferential diagnosisPathological spectrumMolecular testingGranular cell componentPathogenic mutationsTumorPerineurial cellsPIK3CANeoplasmsPerineuriomaMolecular featuresGranular cellsMolecular analysisNeural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis
Gunes I, Bernstein E, Cowper S, Panse G, Pradhan N, Camacho L, Page N, Bundschuh E, Williams A, Carns M, Aren K, Fantus S, Volkmann E, Bukiri H, Correia C, Kolachalama V, Wilson F, Mawe S, Mahoney J, Hinchcliff M. Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis. Arthritis Research & Therapy 2025, 27: 85. PMID: 40217251, PMCID: PMC11987334, DOI: 10.1186/s13075-025-03508-9.Peer-Reviewed Original ResearchConceptsModified Rodnan skin scoreSystemic sclerosisFibrosis scoreHistological parametersDiffuse cutaneous systemic sclerosisInterquartile rangeSystemic sclerosis skin biopsiesRodnan skin scoreCutaneous systemic sclerosisOpen-label trialSkin scorePathological parametersSkin biopsiesBiopsySkin outcomesStudy terminationFibrosisHistological analysisBlinded dermatopathologistStained sectionsSpearman correlationBelumosudilPatientsSkin featuresScores
2024
Insulinoma-associated protein 1: An important marker in eyelid tumors with adnexal features
Kuan-Wen Wang S, Pan S, Panse G, McNiff J, Sinard J, Ko C. Insulinoma-associated protein 1: An important marker in eyelid tumors with adnexal features. Journal Of The American Academy Of Dermatology 2024, 92: 940-941. PMID: 39725215, DOI: 10.1016/j.jaad.2024.10.121.Peer-Reviewed Original Research7418 Xanthoma Disseminatum - A Rare cause of Diabetes Insipidus
Balasubramanian P, Cohen J, Corbin Z, Panse G, Inzucchi S. 7418 Xanthoma Disseminatum - A Rare cause of Diabetes Insipidus. Journal Of The Endocrine Society 2024, 8: bvae163.1380. PMCID: PMC11454384, DOI: 10.1210/jendso/bvae163.1380.Peer-Reviewed Original ResearchCentral diabetes insipidusDiabetes insipidusSystem involvementXanthoma disseminatumOvernight water deprivation testPartial central diabetes insipidusCentral nervous system involvementPituitary stalk involvementDegree of hypopituitarismNon-Langerhans cell histiocytosisVariable degrees of hypopituitarismAnterior pituitary functionResolution of symptomsWater deprivation testNervous system involvementSymptoms of polyuriaMRI pituitaryStalk involvementPituitary involvementHypogonadotropic hypogonadismIV contrastSpontaneous regressionPituitary functionPituitary stalkSerum sodiumTRPS1 expression in MPNST is correlated with PRC2 inactivation and loss of H3K27me3
Lazcano R, Ingram D, Panse G, Lazar A, Wang W, Cloutier J. TRPS1 expression in MPNST is correlated with PRC2 inactivation and loss of H3K27me3. Human Pathology 2024, 151: 105632. PMID: 39084565, DOI: 10.1016/j.humpath.2024.105632.Peer-Reviewed Original ResearchMalignant peripheral nerve sheath tumorTrichorhinophalangeal syndrome type 1TRPS1 expressionPeripheral nerve sheath tumorsNerve sheath tumorsLoss of H3K27me3Sheath tumorsNon-mammary tumorsPRC2 inactivationCellular neurofibromaAtypical neurofibromaImmunohistochemical expressionImmunohistochemical markersMammary originNeurofibromasTumorIntense stainingType 1SchwannomaPOS0824 ARTIFICIAL INTELLIGENCE (DEEP NEURAL NETWORK ANALYSIS) AS A SKIN OUTCOME: RESULTS OF AN OPEN-LABEL BELUMOSUDIL TRIAL IN PATIENTS WITH DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS
Gunes B, Camacho L, Cowper S, Panse G, Page N, Bundschuh E, Williams A, Carns M, Aren K, Pradhan N, Bernstein E, Fantus S, Volkmann E, Bukiri H, Correia C, Wilson F, Mawe S, Mahoney J, Wang R, Hinchcliff M. POS0824 ARTIFICIAL INTELLIGENCE (DEEP NEURAL NETWORK ANALYSIS) AS A SKIN OUTCOME: RESULTS OF AN OPEN-LABEL BELUMOSUDIL TRIAL IN PATIENTS WITH DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS. Annals Of The Rheumatic Diseases 2024, 83: 1046-1047. DOI: 10.1136/annrheumdis-2024-eular.2892.Peer-Reviewed Original Research
Clinical Care
Overview
Gauri Panse, MD, is a dermatopathologist who specializes in diagnosing diseases of the skin, hair, and nails through microscopic evaluation. Dr. Panse examines tissue samples to identify a range of conditions, including inflammatory disorders, autoimmune issues, and skin growths.
As an assistant professor of dermatology at Yale School of Medicine, Dr. Panse focuses on improving diagnostic approaches to both skin and soft tissue diseases. She frequently lectures at national meetings of dermatology, pathology, and dermatopathology societies, and has published extensively on these topics.
Dr. Panse received her medical training from Topiwala National Medical College and Bai Yamunabai Laxman Nair Charitable Hospital in India. She completed a residency in pathology at Baystate Medical Center, Tufts University, followed by a fellowship in bone and soft tissue pathology at M.D. Anderson Cancer Center and a fellowship in dermatopathology at Yale School of Medicine.
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Laboratory for Medicine and Pediatrics (LMP)
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15 York Street, Fl 5th, Rm 5031
New Haven, CT 06510