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Fees

Effective July 1, 2019

CRISPR/CAS

INTERNAL RATES

BASIC RATES:

Design $900
Reagent production, testing  $2,000
Microinjection $4,500
Genotyping $1,000-$2,000

GUARANTEED* RATES:

CRISPR/Cas KO    $9,500
CRISPR/Cas point mutation, simple knockin  $12,000
CRISPR/Cas conditional KO (flox)  (Includes verification of germline transmission) $16,500
Developmental, complex projects inquire
*details available upon project request. Includes genotyping and delivery of founders
Note:  Additional injections will be charged the Basic CRISPR rate

TRANSGENIC MOUSE 

$4750

BAC surcharge: $775
Alternate strain (est.) $850
Genotyping $1,500

GENE TARGETING SERVICE 

ES gene targeting (est; package rate) $16,000

PER-UNIT RATES:

Targeting/Transgenic vector construction $1500-6000
Electroporation, drug selection $1,100
Electroporation, alternate ES strain (e.g. C57Bl/6) $1,250
Expansion of ES colonies, freezing (per clone) $17
Genotyping $2,500
Expansion, freezing alternate ES strain (e.g. C57Bl/6) (per clone) $18
Expansion of positive clones (per clone) $325
Karyotyping (per clone) $325
De novo derivation of ES cells (per clone) $825
Embryonic stem (ES) cells  $375/vial
Mouse embryonic fibroblasts (MEF)  $125/vial
ES cell medium  $275/L (additional for other formulations) 
MEF medium  $125/L

BLASTOCYST INJECTION

C57Bl/6 donor (per blast) $36
Embryo transfer (each) $140
Tissue biopsy for genotyping (each) $8
Deleter mice  $225

CRYOPRESERVATION/REANIMATION

Cryopreservation – Embryo  $125/hr + animal purchase costs 
Cryopreservation - Sperm $500
Strain reanimation (IVF) $900 + animal purchase costs 
Embryo thaw/derivation  $525 + animal purchase costs 

CUSTOM SERVICES (HOURLY)

$110