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CHIRAL Leadership

Principal Investigators

  • Associate Professor of Medicine (General Medicine); Associate Dean for Student Research, MD Program; Co-Director, National Clinician Scholars Program

    Sarwat Chaudhry, MD is a board-certified internist who completed her clinical training at the University of Chicago. She came to Yale for the Robert Wood Johnson Clinical Scholars Program, and now holds a faculty position as Associate Professor of Medicine in the Section of General Medicine. Her work focuses on improving the care and outcomes of hospitalized patients, with a focus on older patients hospitalized for cardiovascular disease. Dr. Chaudhry serves as Associate Dean of Student Research and is Co-Director of the National Clinician Scholars Program at Yale.
  • Associate Professor Term; Chief, Section of Administration, Emergency Medicine; Associate Professor, Department of Emergency Medicine, Emergency Medicine; Scientist, Center for Outcomes Research and Evaluation, Internal Medicine; Co-Director, Emergency Department Administration Fellowship, Emergency Medicine

    Dr. Venkatesh is an Associate Professor and Chief of the Section of Administration in the Department of Emergency Medicine at Yale University. He is also Scientist at the Yale Center for Outcomes Research and Evaluation. He has been funded by the NIH, AHRQ, and the Emergency Medicine Foundation to study health system outcomes and efficiency, and he is supported by the Centers for Medicare and Medicaid Services as co-Principal Investigator of the Emergency Quality Network (E-QUAL) and for the development of the Overall Hospital Quality Star Ratings. He has received over $6 million in grant funding and published over 80 peer-reviewed papers and is senior editor of The Evidence book series. He is national leader within ACEP and SAEM and he serves on expert panels for the National Quality Forum (NQF), Agency for Healthcare Research and Quality (AHRQ) and CMS. His work is also funded by the National Institute of Drug Abuse and the Addiction Policy Forum to advance the quality and delivery of emergency and acute care for opioid use disorder.  Dr. Venkatesh earned his undergraduate degree at Northwestern University. He went on to earn an MBA from Ohio State University before completing medical school at Northwestern University Feinberg School of Medicine. Most recently he completed Emergency Medicine residency at Brigham and Women’s and Massachusetts General Hospitals and the Robert Wood Johnson Clinical Scholars Program here at Yale University. He is originally from Dayton, OH and resides in New Haven.

Investigators

  • Associate Professor of Neurosurgery; Vice Chair of Clinical Affairs, Neurosurgery; Chief, Neurovascular Surgery; Director, Neurovascular/Endovascular Fellowship

    Dr. Charles Matouk, Associate Professor of Neurosurgery and Radiology & Biomedical Imaging, is a cerebrovascular neurosurgeon with expertise in the open and endovascular treatment of vascular disorders of the brain and spinal cord. He completed his certification examination in neurosurgery from the Royal College of Physicians and Surgeons of Canada in 2009. He completed a 2-year clinical fellowship in Endovascular Neurosurgery / Interventional Neuroradiology as well as a Vascular Biology Research Fellowship studying human vascular endothelial cells in health and disease at the University of Toronto. He has special interest in treating brain aneurysms, vascular malformations of the brain and spinal cord, carotid occlusive disease, and acute stroke syndromes. He also has an interest in general neurosurgery including adult-onset hydrocephalus.
  • Assistant Professor of Emergency Medicine

    Dr. Sather’s expertise is in the diagnosis and management of critical illness. Dr. Sather currently serves as the Director of Quality and the Director of Critical Care Operations or the Department. He has been instrumental in the creation of clinical guidelines for the management of critically ill patients within the Yale-New Haven Health System. His research focus is similarly focused on the improvement in critical care delivery, transitions in critical care, and the reduction of diagnostic error.  He is Principal Investigator of a Diagnostic Excellence Initiative award from the Gordon and Betty Moore Foundation to develop a composite measure of diagnostic performance in Pulmonary Embolism.  He was also a project Principal Investigator of the AHRQ funded Patient Safety Learning Laboratory project that applied system engineering and process improvement to inter-hospital transfer care of patients with intracranial hemorrhage. Dr. Sather is also currently involved in trials of early care for septic shock and a study of retrograde endovascular balloon occlusion of the aorta in cardiac arrest.  Dr. Sather is an established educator at the undergraduate and graduate medical education levels as core faculty member of the clinical reasoning curriculum for the School of Medicine, teacher of a popular weekly seminar in clinical reasoning for the EM clerkship, and as faculty lead of the Critical Care Area of Concentration for emergency medicine residents. Dr. Sather in actively engaged in University and Health System service as a member of the Yale School of Medicine Admissions Committee and the Yale-Haven Hospital Mortality Review Committee.
  • Professor of Neurology and Neurosurgery; Executive Director of the NNCTU and Vice Chair for Clinical and Translational Research in the Departments of Neurology and Neurosurgery; Division Chief, Neurocritical Care and Emergency Neurology

    Dr. Kevin Sheth is the founding Chief of the Division of Neurocritical Care & Emergency Neurology. His interests are in the advancement of therapies for acute brain injury such as stroke and brain hemorrhage. He is recognized for his leadership in prevention, acute treatment, and recovery.  In pioneering the development of new strategies to treat brain swelling, his work has changed the fundamental approach to brain injury in the ICU and spurned the creation of new technologies in drug delivery and neuroimaging. His team at Yale has served as a national model for academic critical care neurology units. He is currently the principal investigator for two NIH neuroscience networks, NeuroNEXT and StrokeNet, and three additional RO1/UO1 awards from the NIH. Dr. Sheth has served as PI or co-PI for 8 multicenter clinical trials in stroke, as well as chair for clinical endpoint and data safety monitoring committees for several pivotal studies. He is a winner of the prestigious Robert Siekert Award from the American Heart Association (AHA), the Derek Denny Brown Award from the American Neurological Association and an elected member of the American Society for Clinical Investigation (ASCI). His research has been funded by the NIH, American Academy of Neurology, AHA, and the US Army. Dr. Sheth is the author of over 250 publications and has served on study sections for the NIH, AHA, FDA and NASA. He is an Associate Editor at Neurology and on the editorial boards for Stroke and Neurosurgery. His work has been showcased in The Washington Post, Wall Street Journal, NPR, and CNN.   Finally, Dr. Sheth has formed exciting partnerships with entrepreneurs, pharmaceutical companies, and medical device start-ups to bring forward highly innovative solutions. These efforts have resulted in extensive knowledge of FDA pathways, development of phase I-III drug programs, and implementation of new technology into the clinical workspace. The principal theme of his efforts are towards collaboration and an improved understanding of neurological disease.