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C. Patrick Lusk, PhD

Associate Professor of Cell Biology
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Additional Titles

Co-Director, Molecular Cell Biology, Genetics and Development Track, Cell Biology

Co-Director, Cellular, Molecular, and Quantitative Biology Training Program, Cell Biology

About

Titles

Associate Professor of Cell Biology

Co-Director, Molecular Cell Biology, Genetics and Development Track, Cell Biology; Co-Director, Cellular, Molecular, and Quantitative Biology Training Program, Cell Biology

Biography

Dr. Lusk runs the joint LusKing laboratory with Megan King in the Department of Cell Biology. He is also the co-director of the MCGD graduate training track. He has a long standing interest in fundamental cellular mechanisms of compartmentalization with an emphasis on those that govern the biogenesis of the nuclear envelope and nuclear pore complexes (NPCs). He has been studying the nuclear envelope and nuclear transport since his graduate work at the University of Alberta in Canada and has been trained during his postdoctoral fellowship by Nobel Laureate Günter Blobel at The Rockefeller University. During this time, he (with collaborators/colleagues) has provided substantial insight into how nuclear transport is regulated and how the NPC is assembled. Moreover, he has helped to develop yeast as a model to study integral membrane proteins that reside at the inner nuclear membrane. While it is generally understood that these proteins are essential factors in gene regulation and genome organization, which is reflected by the discovery of the “nuclear envelopathies”, they remain challenging to study. Dr. Lusk is leveraging his expertise in yeast cell biology and genetics with super-resolution and proteomic approaches to illuminate function at the nuclear periphery.

Appointments

Education & Training

Postdoctoral Fellow
The Rockefeller University (2009)
PhD
University of Alberta (2005)
BS
University of Alberta (1998)

Research

Overview

Medical Subject Headings (MeSH)

Nuclear Envelope; Nuclear Pore; Nuclear Pore Complex Proteins

Research at a Glance

Yale Co-Authors

Frequent collaborators of C. Patrick Lusk's published research.

Publications

2024

2023

2022

2021

Get In Touch

Contacts

Academic Office Number
Mailing Address

Cell Biology

PO Box 208002, 333 Cedar Street

New Haven, CT 06520-8002

United States

Administrative Support

Locations

  • Boyer Center for Molecular Medicine

    Lab

    295 Congress Avenue, Ste BCMM 247

    New Haven, CT 06510

  • Boyer Center for Molecular Medicine

    Academic Office

    295 Congress Avenue, Ste BCMM 254B

    New Haven, CT 06510