2009
Bacterial proteins as potential drugs in the treatment of leukemia
Kwan JM, Fialho AM, Kundu M, Thomas J, Hong CS, Gupta T, Chakrabarty AM. Bacterial proteins as potential drugs in the treatment of leukemia. Leukemia Research 2009, 33: 1392-1399. PMID: 19250673, DOI: 10.1016/j.leukres.2009.01.024.Peer-Reviewed Original ResearchConceptsBacterial proteinsSerine/threonine kinaseLeukemia cell linesCaspase recruitment domainCell linesAkt-Ser-473Cell cycle arrestG2/M phaseThreonine kinaseLike domainCARD domainRecruitment domainProtein stabilizationCycle arrestM phaseHL60 cellsProteinActive formPeripheral blood mononuclear cellsBlood mononuclear cellsLeukemia cellsCancer typesAzurinCytotoxic effectsTreatment of leukemia
2001
Pulsed electron paramagnetic resonance methods for macromolecular structure determination
Lakshmi K, Brudvig G. Pulsed electron paramagnetic resonance methods for macromolecular structure determination. Current Opinion In Structural Biology 2001, 11: 523-531. PMID: 11785751, DOI: 10.1016/s0959-440x(00)00242-6.Peer-Reviewed Original ResearchConceptsElectron paramagnetic resonance methodHigh-field EPRParamagnetic resonance methodMacromolecular structure determinationStructure elucidationEPR distance measurementsMacromolecular systemsStructure determinationStructure/function relationshipsRecent applicationsResonance methodMicrowave technologyFunction relationshipsEPRDeterminationRecent developmentsReview articlePowerful toolElucidation
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