2021
Mitochondrial fission in allograft endothelial cells: A novel actionable target
Mullan CW, Pober JS. Mitochondrial fission in allograft endothelial cells: A novel actionable target. American Journal Of Transplantation 2021, 22: 337-338. PMID: 34865296, DOI: 10.1111/ajt.16911.Commentaries, Editorials and Letters
2002
CD2 is a Dominant Target for Allogeneic Responses
Bai Y, Fu S, Honig S, Wang Y, Qin L, Chen D, Bromberg JS. CD2 is a Dominant Target for Allogeneic Responses. American Journal Of Transplantation 2002, 2: 618-626. PMID: 12201362, DOI: 10.1034/j.1600-6143.2002.20706.x.Peer-Reviewed Original ResearchConceptsAlloantigen-driven proliferationIndefinite allograft survivalAntigen-presenting cellsT cellsAllograft survivalCardiac allograft recipientsProlong graft survivalT cell responsesCombination of mAbsIFN-gamma productionAllograft recipientsMAb administrationGraft survivalNK cytotoxicityAllograft rejectionCytokine responsesAllogeneic responseSurvival resultsPotent regulatory moleculesSingle MAbAnti-CD48B cellsMAbs resultsInhibitory mAbsMAbs
1998
ENZYME-LINKED IMMUNOSORBENT ASSAY SPOT DETECTION OF INTERFERON-γ AND INTERLEUKIN 5-PRODUCING CELLS AS AS PREDICTIVE MARKER FOR RENAL ALLOGRAFT FAILURE1
Tary-Lehmann M, Hricik DE, Justice AC, Potter NS, Heeger PS. ENZYME-LINKED IMMUNOSORBENT ASSAY SPOT DETECTION OF INTERFERON-γ AND INTERLEUKIN 5-PRODUCING CELLS AS AS PREDICTIVE MARKER FOR RENAL ALLOGRAFT FAILURE1. Transplantation 1998, 66: 219-224. PMID: 9701268, DOI: 10.1097/00007890-199807270-00014.Peer-Reviewed Original ResearchConceptsIL-5 ratiosGraft dysfunctionPeripheral blood lymphocytesAllograft failureIFN-gammaTransplant recipientsHigh riskIsolated peripheral blood lymphocytesEnzyme-linked immunosorbent spotAcute allograft dysfunctionAcute graft dysfunctionAllograft rejection episodesChronic graft dysfunctionFuture graft lossImproved renal functionRenal allograft recipientsRenal transplant recipientsAcute renal failureProlong graft survivalUseful prognostic markerShort-term survivalAllograft dysfunctionAllograft recipientsGraft functionGraft loss
1994
Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens
Weiner HL, Friedman A, Miller A, Khoury SJ, al-Sabbagh A, Santos L, Sayegh M, Nussenblatt RB, Trentham DE, Hafler DA. Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens. Annual Review Of Immunology 1994, 12: 809-837. PMID: 8011298, DOI: 10.1146/annurev.iy.12.040194.004113.Peer-Reviewed Original ResearchConceptsOrgan-specific autoimmune diseasesExperimental autoimmune encephalomyelitisAntigen-specific fashionOral toleranceRegulatory cellsSuppressive cytokinesAutoimmune diseasesClonal anergyHuman organ-specific autoimmune diseasesGut-associated lymphoid tissueAntigen-nonspecific fashionExperimental autoimmune modelsTh2-type responsePositive clinical effectsProlong graft survivalPeripheral immune toleranceT cell autoreactivityInitial clinical trialsAntigen-induced toleranceActive suppressionOral tolerizationSuppress alloreactivityGraft survivalNOD miceAutoimmune encephalomyelitis
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