2014
Pathology and genetics of pancreatic neoplasms with acinar differentiation
Wood L, Klimstra D. Pathology and genetics of pancreatic neoplasms with acinar differentiation. Seminars In Diagnostic Pathology 2014, 31: 491-497. PMID: 25441307, PMCID: PMC4316670, DOI: 10.1053/j.semdp.2014.08.003.Peer-Reviewed Original ResearchConceptsPancreatic neoplasmsAcinar differentiationAcinar cell carcinomaConventional ductal adenocarcinomaFamily of neoplasmsTherapeutically targetable mutationsAcinar growth patternGranular eosinophilic cytoplasmMolecular dataAcinar neoplasmsGenomic instabilityRare mutationsGenetic alterationsCell carcinomaTargeted mutationEosinophilic cytoplasmPoor prognosisDuctal adenocarcinomaHistological featuresMutationsNeoplastic cellularityNeoplasmsLineage markersUniform nucleiPathological features
2008
Acinar Cell Carcinoma of the Pancreas Metastatic to the Ovary
Vakiani E, Young R, Carcangiu M, Klimstra D. Acinar Cell Carcinoma of the Pancreas Metastatic to the Ovary. The American Journal Of Surgical Pathology 2008, 32: 1540-1545. PMID: 18724247, DOI: 10.1097/pas.0b013e31817a8ebb.Peer-Reviewed Original ResearchConceptsAcinar cell carcinomaOvarian tumorsCell carcinomaCell tumorsDifferential diagnosisMetastatic acinar cell carcinomaCase of acinar cell carcinomaGranular cytoplasmAmount of fibrous stromaEvaluate ovarian tumorsGranulosa cell tumorsSertoli cell tumorAverage patient ageAcinar growth patternPotential diagnostic pitfallsMass of tumorInclusion of antibodiesCarcinoid tumorsImmunohistochemical panelNeuroendocrine neoplasmsAbdominal massPancreatic tumorsNegative immunostainingPatient ageDiagnostic pitfalls
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