2016
A Genetic Test Predicts Providence Brace Success for Adolescent Idiopathic Scoliosis When Failure Is Defined as Progression to >45 Degrees
Bohl DD, Telles CJ, Ruiz FK, Badrinath R, DeLuca PA, Grauer JN. A Genetic Test Predicts Providence Brace Success for Adolescent Idiopathic Scoliosis When Failure Is Defined as Progression to >45 Degrees. Clinical Spine Surgery A Spine Publication 2016, 29: e146-e150. PMID: 27007790, DOI: 10.1097/bsd.0b013e3182aa4ce1.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisPotential confoundingIdiopathic scoliosisGenetic testsRetrospective cohort studyMainstay of treatmentRisk of progressionCohort studyEligible subjectsRetrospective cohortAIS patientsPotential confoundersClinical managementAvailable genetic testsBACKGROUND DATAGenetic predispositionPatientsClinical practiceSaliva samplesScoliScoreProvidence braceGenetic factorsPolygenic fashionScoliosisProgression
2003
A new obesity-prone, glucose-intolerant rat strain (F.DIO)
Levin BE, Dunn-Meynell AA, McMinn JE, Alperovich M, Cunningham-Bussel A, Chua SC. A new obesity-prone, glucose-intolerant rat strain (F.DIO). AJP Regulatory Integrative And Comparative Physiology 2003, 285: r1184-r1191. PMID: 12855420, DOI: 10.1152/ajpregu.00267.2003.Peer-Reviewed Original ResearchConceptsDiet-induced obeseF344 ratsOral glucoseLeptin levelsInsulin responseHigher plasma leptin levelsExaggerated insulin responseLow-fat chowHigher leptin levelsPlasma leptin levelsGreater insulin responseOutbred Sprague-Dawley ratsSprague-Dawley ratsF344 damsDIO ratsFat dietMale ratsF344 malesHigh-energy dietRat strainsMale offspringRatsPolygenic fashionMalesPolygenic mode
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