2016
Different modes of variation for each BG lineage suggest different functions
Chattaway J, Ramirez-Valdez R, Chappell P, Caesar J, Lea S, Kaufman J. Different modes of variation for each BG lineage suggest different functions. Open Biology 2016, 6: 160188. PMID: 27628321, PMCID: PMC5043582, DOI: 10.1098/rsob.160188.Peer-Reviewed Original ResearchConceptsComplementarity-determining region 1BG genesGenomic locationsSequence cassettesSequence diversityChromosome 2Phenotypic variationLipid bindingIntracellular regionImmunoglobulin variableAllelic polymorphismPolymorphic residuesImmune defenceGenesT cellsRegion 1ButyrophilinBG1Co-inhibitionTissue distributionDiversityImmune systemChromosomeHomologuesCDR2
2013
A Mechanistic Basis for the Co-evolution of Chicken Tapasin and Major Histocompatibility Complex Class I (MHC I) Proteins*
van Hateren A, Carter R, Bailey A, Kontouli N, Williams A, Kaufman J, Elliott T. A Mechanistic Basis for the Co-evolution of Chicken Tapasin and Major Histocompatibility Complex Class I (MHC I) Proteins*. Journal Of Biological Chemistry 2013, 288: 32797-32808. PMID: 24078633, PMCID: PMC3820913, DOI: 10.1074/jbc.m113.474031.Peer-Reviewed Original ResearchConceptsMHC-I lociI lociTapasin geneMHC allelesCo-evolutionPeptide binding propertiesMHC-I allelesPolymorphic residuesMechanistic basesCell surface to cytotoxic T cellsAllelesCo-factorMHC-IAffinity peptidesMajor histocompatibility complex class IGenesMaturation efficiencyBinding propertiesMammalsChickenTapasin functionPeptideMHC class I moleculesCo-evolveHistocompatibility complex class I
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