2008
Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition
Fetalvero KM, Zhang P, Shyu M, Young BT, Hwa J, Young RC, Martin KA. Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition. Journal Of Clinical Investigation 2008, 118: 3966-3979. PMID: 19033666, PMCID: PMC2582928, DOI: 10.1172/jci33800.Peer-Reviewed Original ResearchConceptsEnhanced contractile responseContractile responseMyometrial activationConnexin 43Contractile proteinsStrong phasic contractionsMaximal contractile responseHuman myometrial tissueOnset of laborPGI2 analog iloprostSmooth muscle relaxantPregnant human myometriumGap junction protein connexin 43Preterm laborPhasic contractionsPregnant stateProtein connexin 43Contractile agonistsMuscle relaxantsAnalogue iloprostHuman myometriumPGI2 receptorCOX-2Smooth muscleMyometrial tissue
1995
Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle
Nishimoto T, Latifpour J, Wheeler M, Yoshida M, Weiss R. Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle. Journal Of Urology 1995, 153: 1701-1705. PMID: 7715014, DOI: 10.1016/s0022-5347(01)67508-6.Peer-Reviewed Original ResearchConceptsElectrical field stimulationMaximum relaxant responseBeta-adrenergic receptorsMuscle stripsRelaxant responsesRelaxant effectTonic contractionMaximal KCl-induced contractionRat detrusor smooth muscleAge groupsMale Fischer 344 ratsDetrusor muscle stripsEFS-induced contractionsKCl-induced contractionBeta-adrenergic responsivenessDetrusor smooth muscleFischer 344 ratsBeta-adrenergic stimulationAge-dependent alterationsAge-related decreaseCyclic AMP productionDibutyryl cyclic AMPRat detrusorPhasic contractionsBladder detrusorAge-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle
Nishimoto T, Latifpour J, Wheeler M, Yoshida M, Weiss R. Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle. Journal Of Urology 1995, 153: 1701-1705.. DOI: 10.1097/00005392-199505000-00105.Peer-Reviewed Original ResearchElectrical field stimulationMaximum relaxant responseBeta-adrenergic receptorsMuscle stripsRelaxant responsesRelaxant effectTonic contractionMaximal KCl-induced contractionRat detrusor smooth muscleAge groupsCholera toxinMale Fischer 344 ratsDetrusor muscle stripsEFS-induced contractionsKCl-induced contractionBeta-adrenergic responsivenessDetrusor smooth muscleFischer 344 ratsBeta-adrenergic stimulationAge-dependent alterationsAge-related decreaseCyclic AMP productionDibutyryl cyclic AMPRat detrusorPhasic contractions
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