Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective study
Asperen R, la Roi-Teeuw H, van Amstel R, Bos L, Tissing W, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R, Comoretto R, Mizia-Malarz A, Moscatelli A, Sánchez-Martín M, Willems J, Rogerson C, Bennett T, Luo Y, Atreya M, Faustino E, Geva A, Weiss S, Schlapbach L, Sanchez-Pinto L, consortium of ESPNIC A, Caballero M, Margarit A, Campos R, Möller P, Serpe C, Amigoni A, Damps M, Montaguti A, Tardini G, group T, Bubeck-Wardenburg J, Farris R, Hall M, Chong G, Shah S, Khemani R, Stroup E. Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective study. EClinicalMedicine 2023, 65: 102252. PMID: 37842550, PMCID: PMC10570699, DOI: 10.1016/j.eclinm.2023.102252.Peer-Reviewed Original ResearchPaediatric intensive care unitPaediatric cancer patientsLatent class analysisSepsis phenotypesCancer patientsPatient populationInternational multicentre retrospective studyEunice Kennedy Shriver National Institute of Child HealthPaediatric intensive care unit admissionSeverity of organ dysfunctionStem cell transplantationMulticentre retrospective studyOR of deathPhenotype 1Renal replacement therapyNon-cancer patientsPhenotype 2National Institute of Child HealthInstitute of Child HealthIntensive care unitPrecision medicine approachSpecific patient populationsChild healthHigher mortality rateCell transplantation
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply