2004
Regulatory T cells in type 1 diabetes mellitus
Viglietta V, Baecher-Allan C, Hafler A, Gottlieb P. Regulatory T cells in type 1 diabetes mellitus. Current Opinion In Endocrinology Diabetes And Obesity 2004, 11: 85-90. DOI: 10.1097/01.med.0000129641.34639.2e.Peer-Reviewed Original ResearchRegulatory T cellsType 1 diabetes mellitusType 1 diabetesT cellsDiabetes mellitusT lymphocytesHuman type 1 diabetesΒ-cell antigensNK T cellsTh2-type responseMost healthy subjectsReactive T lymphocytesOnset of diseaseInsulin-producing β-cellsAutoimmune conditionsPeripheral toleranceRegulatory cellsPeripheral deletionSpecific immunizationTh2 cytokinesAutoimmune diseasesHealthy subjectsAntigen reactivityHealthy individualsAnergy induction
2001
Involvement of CD1 in Peripheral Deletion of T Lymphocytes Is Independent of NK T Cells
Dao T, Exley M, Mehal W, Tahir S, Snapper S, Taniguchi M, Balk S, Crispe I. Involvement of CD1 in Peripheral Deletion of T Lymphocytes Is Independent of NK T Cells. The Journal Of Immunology 2001, 166: 3090-3097. PMID: 11207260, DOI: 10.4049/jimmunol.166.5.3090.Peer-Reviewed Original ResearchConceptsNK T cellsPeripheral T cell deletionT cell deletionT cellsCell deletionCD1-deficient miceBone marrow chimerasExpression of CD1T cell activationMHC-like moleculesNonlymphoid organsLymph nodesPeripheral deletionNormal miceT lymphocytesCell activationMutant mouse linesMouse linesAttenuated accumulationMiceLymphocytesNovel roleCD1Ab resultsLiver
1999
Selective retention of activated CD8+ T cells by the normal liver.
Mehal W, Juedes A, Crispe I. Selective retention of activated CD8+ T cells by the normal liver. The Journal Of Immunology 1999, 163: 3202-10. PMID: 10477588, DOI: 10.4049/jimmunol.163.6.3202.Peer-Reviewed Original Research
1998
TCR ligation on CD8+ T cells creates double-negative cells in vivo.
Mehal W, Crispe I. TCR ligation on CD8+ T cells creates double-negative cells in vivo. The Journal Of Immunology 1998, 161: 1686-93. PMID: 9712032, DOI: 10.4049/jimmunol.161.4.1686.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, Polyomavirus TransformingCD8-Positive T-LymphocytesClonal Deletionfas ReceptorHistocompatibility Antigens Class IImmunophenotypingInjections, IntraperitonealLiverLymph NodesLymphocyte CountLymphocyte DepletionMiceMice, Inbred C57BLMice, Inbred MRL lprMice, TransgenicReceptors, Antigen, T-Cell, alpha-betaT-Lymphocyte Subsets
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