2014
Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study
Tylee DS, Chandler SD, Nievergelt CM, Liu X, Pazol J, Woelk CH, Lohr JB, Kremen WS, Investigators M, Baker D, Glatt S, Tsuang M. Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study. Psychoneuroendocrinology 2014, 51: 472-494. PMID: 25311155, PMCID: PMC4199086, DOI: 10.1016/j.psyneuen.2014.09.024.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderPeripheral bloodBiomarker panelStress disorderPilot studyPeripheral blood biomarkersHigh-risk individualsPeripheral blood samplesPeripheral blood cellsExpression levelsDiagnostic biomarker panelGene expression levelsTrauma-exposed individualsBlood biomarkersBlood samplesGene expression biomarkersBiomarker profilesDiagnostic utilityBrain tissueDiagnostic panelBlood cellsBloodFull-length gene transcriptsBiomarkersDisorders
2012
Biomarkers in idiopathic pulmonary fibrosis
Zhang Y, Kaminski N. Biomarkers in idiopathic pulmonary fibrosis. Current Opinion In Pulmonary Medicine 2012, 18: 441-446. PMID: 22847105, PMCID: PMC4165635, DOI: 10.1097/mcp.0b013e328356d03c.Peer-Reviewed Original ResearchConceptsIdiopathic pulmonary fibrosisPeripheral blood biomarkersPulmonary fibrosisBlood biomarkersDisease presenceMultiple clinical contextsPeripheral bloodPredictive biomarkersGene polymorphismsLarger studyDrug studiesOutcome trajectoriesPrediction ruleClinical contextBiomarkersMolecular biomarkersMultiple studiesPatientsFibrosisSufficient evidenceOutcomesProtein markersConvincing evidenceRecent studiesMarkers
2008
MMP1 and MMP7 as Potential Peripheral Blood Biomarkers in Idiopathic Pulmonary Fibrosis
Rosas IO, Richards TJ, Konishi K, Zhang Y, Gibson K, Lokshin AE, Lindell KO, Cisneros J, MacDonald SD, Pardo A, Sciurba F, Dauber J, Selman M, Gochuico BR, Kaminski N. MMP1 and MMP7 as Potential Peripheral Blood Biomarkers in Idiopathic Pulmonary Fibrosis. PLOS Medicine 2008, 5: e93. PMID: 18447576, PMCID: PMC2346504, DOI: 10.1371/journal.pmed.0050093.Peer-Reviewed Original ResearchConceptsIdiopathic pulmonary fibrosisInterstitial lung diseaseSubclinical interstitial lung diseasePulmonary fibrosisLung diseaseIPF patientsChronic progressive fibrotic lung diseaseControl individualsAsymptomatic interstitial lung diseaseProgressive fibrotic lung diseaseChronic obstructive pulmonary diseasePotential peripheral blood biomarkerChronic hypersensitivity pneumonitisPeripheral blood biomarkersChronic lung diseaseObstructive pulmonary diseaseFibrotic lung diseaseBronchoalveolar lavage fluidIndependent validation cohortFamilial pulmonary fibrosisProtein signaturesPulmonary diseaseSubstantial morbidityHypersensitivity pneumonitisLavage fluid
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