2007
Fibroblast Growth Factors
Murakami M, Elfenbein A, Simons M. Fibroblast Growth Factors. 2007, 291-303. DOI: 10.1017/cbo9780511546198.035.Peer-Reviewed Original ResearchFGF genesFibroblast growth factorGene duplicationGrowth factorBovine brainFGF receptor genesBasic isoelectric pointBALB/c 3T3 fibroblast cellsEarly vertebratesCaenorhabditis elegansDrosophila melanogasterFruit flyFGFR genesBasic fibroblast growth factorAcidic fibroblast growth factorGenesHeparin-Sepharose chromatographyReceptor geneProteinNomenclature CommitteeSepharose chromatographyFibroblast cellsBasic proteinMyelin basic proteinDuplication
1996
Angiogenesis induced by acidic fibroblast growth factor as an alternative method of revascularization for chronic myocardial ischemia
Sellke F, Li J, Stamler A, Lopez J, Thomas K, Simons M. Angiogenesis induced by acidic fibroblast growth factor as an alternative method of revascularization for chronic myocardial ischemia. Surgery 1996, 120: 182-188. PMID: 8751581, DOI: 10.1016/s0039-6060(96)80286-8.Peer-Reviewed Original ResearchConceptsCollateral-dependent LCx regionAcidic fibroblast growth factorFibroblast growth factorLCx regionBlood flowSodium nitroprussideProximal left circumflex coronary arterySevere coronary artery diseaseLeft circumflex coronary arteryGrowth factorCoronary arterial microvesselsCoronary microvascular reactivityProximal (<b>d</b>) LCX arteryEndothelium-dependent mechanismEndothelium-dependent relaxationCircumflex coronary arteryCollateral-dependent myocardiumCoronary artery diseaseTreatment of patientsGuanylate cyclase activators sodium nitroprussideChronic myocardial ischemiaAdenylate cyclase activator forskolinPeriadventitial administrationCyclase activator forskolinMicrovascular reactivity
1992
Acidic fibroblast growth factor-Pseudomonas exotoxin chimeric protein elicits antiangiogenic effects on endothelial cells.
Merwin J, Lynch M, Madri J, Pastan I, Siegall C. Acidic fibroblast growth factor-Pseudomonas exotoxin chimeric protein elicits antiangiogenic effects on endothelial cells. Cancer Research 1992, 52: 4995-5001. PMID: 1381275.Peer-Reviewed Original ResearchMeSH KeywordsADP Ribose TransferasesAmino Acid SequenceAnimalsBacterial ToxinsCell MovementCell SurvivalCells, CulturedEndothelium, VascularExotoxinsFibroblast Growth Factor 1In Vitro TechniquesMolecular Sequence DataNeovascularization, PathologicRatsRats, Inbred StrainsReceptors, Cell SurfaceReceptors, Fibroblast Growth FactorRecombinant Fusion ProteinsVirulence FactorsConceptsGrowth factor beta 1Endothelial cellsChimeric toxinBeta 1Inhibitory effectDose-dependent toxic effectAnti-angiogenic agentsMicrovascular endothelial cellsAcidic fibroblast growth factorFibroblast growth factorSignificant inhibitory effectMicrovascular endotheliumAntiangiogenic effectsPseudomonas exotoxinTumor cell linesAntimigratory effectsGrowth factorAngiogenic responseProtein synthesisCell linesFGF receptorsToxic effectsCell deathEndotheliumCell viability analysisEntubulization Repair of Severed Cavernous Nerves in the Rat Resulting in Return of Erectile Function
Ball R, Lipton S, Dreyer E, Richie J, Vickers M. Entubulization Repair of Severed Cavernous Nerves in the Rat Resulting in Return of Erectile Function. Journal Of Urology 1992, 148: 211-215. PMID: 1613871, DOI: 10.1016/s0022-5347(17)36555-2.Peer-Reviewed Original ResearchConceptsCavernous nerveErectile functionMale Sprague-Dawley ratsNerve growthImmediate nerve reconstructionNerve ablation groupNerve graft groupNerve graft repairRadical pelvic surgerySprague-Dawley ratsImmediate microsurgical reconstructionElectrical stimulation studiesDirect electrical stimulationAcidic fibroblast growth factorFibroblast growth factorNerve ablationSurgical groupGraft repairAblation groupCavernosal nerveGraft groupNerve reconstructionNerve stumpErectile dysfunctionPelvic surgery
1989
Acidic Fibroblast Growth Factor Enhances Peripheral Nerve Regeneration in Vivo
Cordeiro P, Seckel B, Lipton S, D'Amore P, Wagner J, Madison R. Acidic Fibroblast Growth Factor Enhances Peripheral Nerve Regeneration in Vivo. Plastic & Reconstructive Surgery 1989, 83: 1013-1019. PMID: 2727148, DOI: 10.1097/00006534-198906000-00014.Peer-Reviewed Original ResearchConceptsPeripheral nerve regenerationAcidic fibroblast growth factorNerve regenerationGrowth factorNerve guidesEffect of aFGFNerve growth factorNerve guide tubesFibroblast growth factorMotor neuronsPrimary sensoryAxonal branchingMyelinated axonsExperimental modelAxonsVivoFactorsGreater numberNeurons
1988
Acidic fibroblast growth factor enhances regeneration of processes by postnatal mammalian retinal ganglion cells in culture.
Lipton S, Wagner J, Madison R, D'Amore P. Acidic fibroblast growth factor enhances regeneration of processes by postnatal mammalian retinal ganglion cells in culture. Proceedings Of The National Academy Of Sciences Of The United States Of America 1988, 85: 2388-2392. PMID: 3353388, PMCID: PMC279998, DOI: 10.1073/pnas.85.7.2388.Peer-Reviewed Original ResearchConceptsRat retinal ganglion cellsBasic fibroblast growth factorAcidic fibroblast growth factorRetinal ganglion cellsFibroblast growth factorGlial cellsGrowth factorProcess outgrowthGanglion cellsPostnatal rat retinal ganglion cellsMammalian retinal ganglion cellsOutgrowth of processesGlial fibrillary acidic proteinEffect of aFGFMammalian central nervous systemMammalian central neuronsRegeneration of processesFibrillary acidic proteinCentral nervous systemPeptide growth factorsRGC survivalHumoral effectsHeparin-like moleculesCentral neuronsAddition of heparin
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