Real world treatment patterns for recurrent and metastatic head and neck cancer in the post-KEYNOTE 048 era
Lee D, Pan A, Yaskolko M, Chiorazzi M, Bhatia A, Burtness B, Ishizuka J. Real world treatment patterns for recurrent and metastatic head and neck cancer in the post-KEYNOTE 048 era. Frontiers In Oncology 2025, 15: 1577509. PMID: 40416868, PMCID: PMC12099209, DOI: 10.3389/fonc.2025.1577509.Peer-Reviewed Original ResearchHead and neck squamous cell carcinomaCombined positive scoreAnti-PD1 monotherapyMetastatic head and neck squamous cell carcinomaOral cavity primariesMetastatic head and neck cancerNon-HPV-associated tumorsPatients treated first-lineToxicity of combined treatmentNeck squamous cell carcinomaReal-world treatment patternsHead and neck cancerFlatiron Health databaseAnti-PD1 therapyChemotherapy improves survivalHPV-associated diseasesFirst-line treatmentSquamous cell carcinomaLog-rank testSubgroup of patientsKaplan-Meier curvesTreatment group differencesKEYNOTE-048Non-HPVAnti-PD1
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