2020
Impact of depressive symptoms on self-perceived severity of autonomic dysfunction in multiple system atrophy: relevance for patient-reported outcomes in clinical trials
Martinez J, Palma JA, Norcliffe-Kaufmann L, Garakani A, Kaufmann H. Impact of depressive symptoms on self-perceived severity of autonomic dysfunction in multiple system atrophy: relevance for patient-reported outcomes in clinical trials. Clinical Autonomic Research 2020, 30: 215-221. PMID: 32246226, PMCID: PMC7341538, DOI: 10.1007/s10286-020-00681-6.Peer-Reviewed Original ResearchConceptsMultiple system atrophyOrthostatic Hypotension QuestionnaireSymptoms of depressionOrthostatic hypotensionAutonomic dysfunctionDepressive symptomsSelf-perceived severityAutonomic symptomsSystem atrophyDepression scoresOHQ scoresOrthostatic blood pressure fallUnified MSA Rating ScaleProbable multiple system atrophyComposite Autonomic Symptom ScoreBlood pressure fallResultsFifty-eight patientsSystolic blood pressureZung depression scorePatient-reported outcomesAutonomic symptom scoreClinical trial designMultivariable regression modelsQuality of lifeConclusionsIn patients
2017
A randomized study on the effect of modified behavioral activation treatment for depressive symptoms in rural left-behind elderly
Xie J, He G, Ding S, Pan C, Zhang X, Zhou J, Iennaco JD. A randomized study on the effect of modified behavioral activation treatment for depressive symptoms in rural left-behind elderly. Psychotherapy Research 2017, 29: 372-382. PMID: 28838290, DOI: 10.1080/10503307.2017.1364444.Peer-Reviewed Original ResearchConceptsBeck Anxiety InventoryIntervention groupDepressive symptomsControl groupRandomized studyRegular treatmentDepression symptomsChinese Clinical Trial RegistryGeriatric Depression Scale scoreClinical Trials RegistryDepression Scale scoresBehavioral Activation TreatmentTrials RegistryRegular careModerate depressionTreatment interventionsScale scoreOHQ scoresOxford Happiness QuestionnaireSymptomsMental healthElderly peopleAnxiety InventoryInterventionGreater reduction
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