2013
Use of touch imprint cytology as a simple method to enrich tumor cells for molecular analysis
Dogan S, Becker J, Rekhtman N, Tang L, Nafa K, Ladanyi M, Klimstra D. Use of touch imprint cytology as a simple method to enrich tumor cells for molecular analysis. Cancer Cytopathology 2013, 121: 354-360. PMID: 23576371, DOI: 10.1002/cncy.21292.Peer-Reviewed Original ResearchConceptsTouch imprintsWhole-tumor samplesTumor cellsCarcinoma samplesKRAS exon 2 mutationsNeoplastic cellsTumor-enriched samplesExon 2 mutationsPercentage of carcinoma cellsTouch imprint cytologyKRAS gene mutationsEpithelial tumor cellsFalse-negative resultsImprint cytologyTP slidesNonneoplastic epitheliumTumor DNAMesenchymal stromaMutant to wild-typeGene mutationsLight microscopyNonneoplastic cellsCarcinoma cellsDirect sequencingSanger sequencing
2011
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
Kostic A, Gevers D, Pedamallu C, Michaud M, Duke F, Earl A, Ojesina A, Jung J, Bass A, Tabernero J, Baselga J, Liu C, Shivdasani R, Ogino S, Birren B, Huttenhower C, Garrett W, Meyerson M. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Research 2011, 22: 292-298. PMID: 22009990, PMCID: PMC3266036, DOI: 10.1101/gr.126573.111.Peer-Reviewed Original ResearchConceptsColorectal carcinomaColorectal carcinoma pathogenesisColorectal tumorsCarcinomaTumor microenvironmentTumor/normal pairsNonneoplastic cellsCancer cellsWhole genome sequencesPrecise roleTumorsMicrobiotaRDNA sequence analysisQuantitative PCRFurther investigationComplex communitiesGenome sequenceGenomic analysisSequence analysisFirmicutes phylumFusobacteriaNormal pairsCellsDiverse collectionDNA pairs
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