Use of touch imprint cytology as a simple method to enrich tumor cells for molecular analysis
Dogan S, Becker J, Rekhtman N, Tang L, Nafa K, Ladanyi M, Klimstra D. Use of touch imprint cytology as a simple method to enrich tumor cells for molecular analysis. Cancer Cytopathology 2013, 121: 354-360. PMID: 23576371, DOI: 10.1002/cncy.21292.Peer-Reviewed Original ResearchConceptsTouch imprintsWhole-tumor samplesTumor cellsCarcinoma samplesKRAS exon 2 mutationsNeoplastic cellsTumor-enriched samplesExon 2 mutationsPercentage of carcinoma cellsTouch imprint cytologyKRAS gene mutationsEpithelial tumor cellsFalse-negative resultsImprint cytologyTP slidesNonneoplastic epitheliumTumor DNAMesenchymal stromaMutant to wild-typeGene mutationsLight microscopyNonneoplastic cellsCarcinoma cellsDirect sequencingSanger sequencing
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