2023
Type 2 Dendritic Cells Orchestrate a Local Immune Circuit to Confer Antimetastatic Immunity
Weizman O, Luyten S, Krykbaeva I, Song E, Mao T, Bosenberg M, Iwasaki A. Type 2 Dendritic Cells Orchestrate a Local Immune Circuit to Confer Antimetastatic Immunity. The Journal Of Immunology 2023, 210: 1146-1155. PMID: 36881866, PMCID: PMC10067787, DOI: 10.4049/jimmunol.2200697.Peer-Reviewed Original ResearchConceptsType 2 dendritic cellsMetastatic burdenImmune circuitsDendritic cellsConventional type 2 dendritic cellsSyngeneic murine melanomaNK cell compartmentImmune cell responsesColon cancer modelEarly metastatic seedingMetastatic controlTranscription factor IRF3DC populationsNK cellsProinflammatory cytokinesNucleic acid sensingPrimary tumorEffector responsesMetastatic spreadDisease outcomeIntracardiac injectionT cellsInitial immunityTissue-specific ablationCancer model
1993
Phenotypic and Functional Analysis of Expanded Natural Killer Cell Subpopulations in Hodgkin’s Disease Patients Treated with Lymphoid Irradiation
Macklis R, Mauch P, Thompson L, Burakoff S, Smith B. Phenotypic and Functional Analysis of Expanded Natural Killer Cell Subpopulations in Hodgkin’s Disease Patients Treated with Lymphoid Irradiation. Oncology 1993, 50: 323-328. PMID: 8497384, DOI: 10.1159/000227203.Peer-Reviewed Original ResearchConceptsNK cell subsetsNK cell compartmentHodgkin's disease patientsDisease patientsLymphoid irradiationNK cellsCell subsetsNatural killer cell subpopulationsSpecific NK cell subsetsLong-term immunosuppressionNK cell assaysCell compartmentSignificant changesCell subpopulationsPatientsCytometric cell sortingLytic activityCell assayImmunophenotypeCell sortingCytotoxicity spectrumImmunosuppressionCellsSubsetCompartments
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