2020
CXCL12 Attracts Bone Marrow-Derived Cells to Uterine Leiomyomas
Moridi I, Mamillapalli R, Kodaman PH, Habata S, Dang T, Taylor HS. CXCL12 Attracts Bone Marrow-Derived Cells to Uterine Leiomyomas. Reproductive Sciences 2020, 27: 1724-1730. PMID: 32020550, DOI: 10.1007/s43032-020-00166-x.Peer-Reviewed Original ResearchConceptsBone marrow-derived cellsMarrow-derived cellsExpression of CXCL12Uterine leiomyomaLeiomyoma growthCommon benign gynecologic tumorsNormal myometriumEngraftment of BMDCsBenign gynecologic tumorsCXCR4 antagonist AMD3100Myometrium of womenStem/progenitor cellsUterine myomaGynecologic tumorsMyoma cellsAntagonist AMD3100CXCR4 expressionControl myometriumReproductive ageUterine diseaseMouse uterusCurrent evidenceLeiomyomaBone marrowMyometrium
2001
Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus
Sozen I, Senturk L, Arici A. Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus. Fertility And Sterility 2001, 76: 792-796. PMID: 11591415, DOI: 10.1016/s0015-0282(01)02378-0.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1Leiomyomatous uterusMacrophage countGonadotropin-releasing hormone agonistDirect paracrine effectChemotactic protein-1 productionMCP-1 levelsChemotactic protein-1MCP-1 stainingCross-sectional studyMyometrium of womenMCP-1 expressionMonocyte chemotactic protein-1 productionMCP-1 protein expressionUniversity Medical CenterProtein-1 productionGnRH agonistHormone agonistMacrophage infiltrationMedical CenterMAIN OUTCOMEImmunohistochemical analysisLeiomyoma cellsParacrine effectsGnRH
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