CXCL12 Attracts Bone Marrow-Derived Cells to Uterine Leiomyomas
Moridi I, Mamillapalli R, Kodaman PH, Habata S, Dang T, Taylor HS. CXCL12 Attracts Bone Marrow-Derived Cells to Uterine Leiomyomas. Reproductive Sciences 2020, 27: 1724-1730. PMID: 32020550, DOI: 10.1007/s43032-020-00166-x.Peer-Reviewed Original ResearchConceptsBone marrow-derived cellsMarrow-derived cellsExpression of CXCL12Uterine leiomyomaLeiomyoma growthCommon benign gynecologic tumorsNormal myometriumEngraftment of BMDCsBenign gynecologic tumorsCXCR4 antagonist AMD3100Myometrium of womenStem/progenitor cellsUterine myomaGynecologic tumorsMyoma cellsAntagonist AMD3100CXCR4 expressionControl myometriumReproductive ageUterine diseaseMouse uterusCurrent evidenceLeiomyomaBone marrowMyometrium
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