Neuronal and astrocytic cells, obtained after differentiation of human neural GFAP-positive progenitors, present heterogeneous expression of PrPc
Witusik M, Gresner S, Hulas-Bigoszewska K, Krynska B, Azizi S, Liberski P, Brown P, Rieske P. Neuronal and astrocytic cells, obtained after differentiation of human neural GFAP-positive progenitors, present heterogeneous expression of PrPc. Brain Research 2007, 1186: 65-73. PMID: 17996224, DOI: 10.1016/j.brainres.2007.10.039.Peer-Reviewed Original ResearchConceptsProgenitor cellsCharacteristics of stem/progenitor cellsCell differentiationMultiplex PCR assayNeuronal cellsExpression of PrPcExpression of PrP(CCellular isoformGFAP-positive cellsIn vitro modelIn vivo studiesUndifferentiated cell populationsPrion proteinWestern blot analysisStem/progenitor cellsHeterogeneous expressionGlial cellsDifferentiated cellsPhysiological roleCell populationsBlot analysisHuman neurogenesisAstrocytic cellsExpression levelsIn vitro
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