Cardioprotection Using Strain-Guided Management of Potentially Cardiotoxic Cancer Therapy 3-Year Results of the SUCCOUR Trial
Negishi T, Thavendiranathan P, Penicka M, Lemieux J, Murbraech K, Miyazaki S, Shirazi M, Santoro C, Cho G, Popescu B, Kosmala W, Costello B, la Gerche A, Mottram P, Thomas L, Seldrum S, Hristova K, Bansal M, Kurosawa K, Fukuda N, Yamada H, Izumo M, Tajiri K, Sinski M, Vinereanu D, Shkolnik E, Banchs J, Kutty S, Negishi K, Marwick T. Cardioprotection Using Strain-Guided Management of Potentially Cardiotoxic Cancer Therapy 3-Year Results of the SUCCOUR Trial. JACC Cardiovascular Imaging 2022, 16: 269-278. PMID: 36435732, DOI: 10.1016/j.jcmg.2022.10.010.Peer-Reviewed Original ResearchConceptsGlobal longitudinal strainCancer therapeutics-related cardiac dysfunctionCardiac dysfunctionCardiotoxic chemotherapyHeart failureMulticenter prospective randomized controlled trialPatients treated with anthracyclinesProspective randomized controlled trialsBaseline to 3 yearsLeft ventricular functionRandomized Controlled TrialsChemotherapy regimenLV dysfunctionVentricular functionBreast cancerFollow-upDiabetes mellitusChemotherapyLongitudinal strainPatientsRisk factorsCardioprotectionDysfunctionCancerAnthracyclines
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