2023
CADASIL mice are characterized by simultaneous metabolic and vascular stress
Wei Z, Li Y, Chen L, Liu H, Yao M, Xu J, Louvi A, Duan W, Lu H. CADASIL mice are characterized by simultaneous metabolic and vascular stress. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/2649.Peer-Reviewed Original ResearchCADASIL miceMouse modelMouse model of CADASILVascular stressNon-contrast MRI techniqueImpaired cerebrovascular reactivityMicrovascular dysfunctionTherapeutic trialsCerebrovascular reactivityMonogenic conditionsVascular pathologyLacunar strokeMRI techniquesMiceCADASILElevated oxygen consumptionPathologyOxygen consumptionVascular cognitive impairmentCognitive impairment
2020
Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy
Liu W, Deacon J, Yan H, Sun B, Liu Y, Hegan D, Li Q, Coman D, Parent M, Hyder F, Roberts K, Nath R, Tillement O, Engelman D, Glazer P. Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy. Translational Oncology 2020, 13: 100839. PMID: 32763504, PMCID: PMC7408331, DOI: 10.1016/j.tranon.2020.100839.Peer-Reviewed Original ResearchHuman lung cancer cellsA549 human lung cancer cellsMolecular MRI techniqueTumor-bearing miceLung cancer cellsClonogenic survival assaysVivo radiosensitizationRadiation therapySolid tumorsTumor cell metabolismTumorsEnhanced radiosensitivityTumor cellsMR imagingSurvival assaysMRI techniquesCancer cellsTreatment planningRadiotherapyTumor coreGeneral hallmarkRadiotherapy treatment planningRadiosensitivityPeptide deliveryDelivery
2019
MRI of the Male Pelvic Floor.
Lakhoo J, Khatri G, Elsayed RF, Chernyak V, Olpin J, Steiner A, Tammisetti VS, Sundaram KM, Arora SS. MRI of the Male Pelvic Floor. RadioGraphics 2019, 39: 2003-2022. PMID: 31697623, DOI: 10.1148/rg.2019190064.Peer-Reviewed Original ResearchConceptsPelvic floorSexual dysfunctionDynamic MRI featuresPelvic floor disordersMale pelvic floorPelvic floor anatomyPelvic floor structuresIncreased toneFemale pelvic floorAnal sphincterChronic painTreatment failureGastrointestinal disordersAnorectal disordersMRI featuresMR defecographyPelvic organsSex-specific differencesPathophysiologic disordersOnline supplemental materialPelvic musculaturePostsurgical functionDysfunctionFemale pelvisMRI techniques
2017
Advanced imaging in acute ischemic stroke.
Kilburg C, Scott McNally J, de Havenon A, Taussky P, Kalani MY, Park MS. Advanced imaging in acute ischemic stroke. Neurosurgical FOCUS 2017, 42: e10. PMID: 28366054, DOI: 10.3171/2017.1.focus16503.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeLarge vessel occlusionTranscranial Doppler ultrasonographyCT angiographyVessel wall MRIMR angiographyIschemic strokeDoppler ultrasonographyVessel occlusionMRI techniquesCollateral blood flowImaging modalitiesConventional CTCharacteristics of lesionsFour-dimensional CT angiographyClot burdenCryptogenic strokeAcute settingStroke treatmentPatent foramenOccult lesionsInvasive alternativeBlood flowNew imaging modalityNatural history
2016
Magnetic resonance imaging patterns of treatment-related toxicity in the pediatric brain: an update and review of the literature
Rossi Espagnet M, Pasquini L, Napolitano A, Cacchione A, Mastronuzzi A, Caruso R, Tomà P, Longo D. Magnetic resonance imaging patterns of treatment-related toxicity in the pediatric brain: an update and review of the literature. Pediatric Radiology 2016, 47: 633-648. PMID: 27933410, DOI: 10.1007/s00247-016-3750-4.Peer-Reviewed Original ResearchConceptsMRI patternBrain regionsMagnetic resonance imaging patternTreatment-related toxicityTreatment-related neurotoxicityApplication of advanced MRI techniquesLife-threatening clinical conditionBrain injuryAdvanced MRI techniquesSpecific treatment protocolsRecurrent diseaseMechanism of actionDiagnostic challengeTherapeutic managementBrain toxicityDifferential diagnosisNeuroradiological findingsRadiological appearanceClinical conditionsSpecific toxic effectsTreatment protocolsPediatric brainMRI techniquesImmediate recognitionClinical timeInterrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid Hemorrhage
Zafar SF, Westover MB, Gaspard N, Gilmore EJ, Foreman BP, O'Connor KL, Rosenthal ES. Interrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid Hemorrhage. Journal Of Clinical Neurophysiology 2016, 33: 235-240. PMID: 27258447, PMCID: PMC4894325, DOI: 10.1097/wnp.0000000000000276.Peer-Reviewed Original ResearchConceptsDelayed ischemic eventsCerebral infarctionNeurologic declineSubarachnoid hemorrhageConsensus definitionIschemic eventsCerebral ischemiaClinical trialsInterrater agreementPerfect overall agreementRadiographic cerebral infarctionPercent of patientsAneurysmal subarachnoid hemorrhageFuture large-scale studiesSuccessful clinical trialsMotor scoresMotor declineOutcome studiesInfarctionIschemiaType 1HemorrhageCT imagingLarge-scale studiesMRI techniques
1998
Regional Ischemia and Ischemic Injury in Patients With Acute Middle Cerebral Artery Stroke as Defined by Early Diffusion-Weighted and Perfusion-Weighted MRI
Rordorf G, Koroshetz W, Copen W, Cramer S, Schaefer P, Budzik R, Schwamm L, Buonanno F, Sorensen A, Gonzalez G. Regional Ischemia and Ischemic Injury in Patients With Acute Middle Cerebral Artery Stroke as Defined by Early Diffusion-Weighted and Perfusion-Weighted MRI. Stroke 1998, 29: 939-943. PMID: 9596239, DOI: 10.1161/01.str.29.5.939.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAged, 80 and overArterial Occlusive DiseasesBrain IschemiaCerebral ArteriesCerebral InfarctionCerebrovascular CirculationCerebrovascular DisordersDiffusionFemaleHumansMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMiddle AgedPerfusionReperfusion InjuryConceptsPerfusion-weighted imagingMiddle cerebral artery strokeDiffusion-weighted imagingCerebral blood volumeMCA strokeArtery strokeMR angiographyCBV abnormalityRegional ischemiaAcute middle cerebral artery strokeInitial diffusion-weighted imagingAcute stroke syndromeDistal branch occlusionDWI lesion volumeInitial DWI lesionMCA stem occlusionGroup 2 patientsMRI techniquesFinal infarct sizeFinal infarct volumeHours of onsetIntravenous contrast bolusAbnormal tissue perfusionProgression of infarctionPerfusion-weighted MRI
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