2010
ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish
Ren B, Deng Y, Mukhopadhyay A, Lanahan AA, Zhuang ZW, Moodie KL, Mulligan-Kehoe MJ, Byzova TV, Peterson RT, Simons M. ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish. Journal Of Clinical Investigation 2010, 120: 1217-1228. PMID: 20237411, PMCID: PMC2846043, DOI: 10.1172/jci39837.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAnimalsArteriesCarrier ProteinsMaleMiceMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3MorphogenesisNeovascularization, PhysiologicNeuropeptidesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2ZebrafishZebrafish Proteins
2007
AIP1 Functions As An Endogenous Inhibitor of VEGFR2‐dependent Angiogenesis
Zhang H, He Y, Luo D, Min W. AIP1 Functions As An Endogenous Inhibitor of VEGFR2‐dependent Angiogenesis. The FASEB Journal 2007, 21: a14-a15. DOI: 10.1096/fasebj.21.5.a14-d.Peer-Reviewed Original ResearchAIP1 functionsRas-GAPEndogenous angiogenic inhibitorsC2 domainNovel memberEndothelial cell apoptosisAIP1Further mechanistic studiesVEGF-VEGFR2 signalingSignalingCell apoptosisTube formationEndogenous inhibitorMouse ECsAngiogenesis modelTumor progressionMice exhibitGross growthAngiogenic inhibitorsMechanistic studiesVEGFR2AngiogenesisBreedingInhibitorsEndocytosis
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