Incidence, Prevalence, and Stability of Remission in Individuals With Clinical High Risk for Psychosis
Seitz-Holland J, Jacobs G, Reinen J, Mathalon D, Corcoran C, Reichenberg A, Vangel M, Glynn R, Penzel N, Cho K, Castro E, Haidar A, Addington J, Kapur T, Bouix S, Bearden C, Kane J, McGorry P, Woods S, Nelson B, Kahn R, Shenton M, Cecchi G, Pasternak O. Incidence, Prevalence, and Stability of Remission in Individuals With Clinical High Risk for Psychosis. JAMA Network Open 2025, 8: e2525644. PMID: 40762913, PMCID: PMC12326281, DOI: 10.1001/jamanetworkopen.2025.25644.Peer-Reviewed Original ResearchConceptsClinical high riskClinical high-risk statusAssociated with higher likelihoodModified Global AssessmentLikelihood of remissionRemission criteriaPositive symptomsGlobal Assessment of FunctioningScale of Prodromal SymptomsRemission incidenceModified Global Assessment of FunctioningAssessment of functioningFollow-upStability of remissionHigh riskHigher likelihood of remissionAntidepressant medicationFunctional remissionCognitive variablesCognitive performanceMain OutcomesClinical servicesStudy 3Follow-up visitCohort study
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