2022
Cerebral arterial and ventricular morphology of the dogfish (Squalus acanthias), American bullfrog (Rana catesbeiana), and green iguana (Iguana iguana): Arterial high‐resolution micro‐CT, dissection, and radiography study
Kier E, Conlogue G, VanHouten J. Cerebral arterial and ventricular morphology of the dogfish (Squalus acanthias), American bullfrog (Rana catesbeiana), and green iguana (Iguana iguana): Arterial high‐resolution micro‐CT, dissection, and radiography study. The Anatomical Record 2022, 306: 2015-2029. PMID: 35778853, DOI: 10.1002/ar.25028.Peer-Reviewed Original ResearchConceptsMicro-CT imagesHigh-resolution micro-CTMicro-CTMicro-computed tomography (CT) imagingMicro-CT imagingArterial morphologyVenous cerebral circulationSequential displayGreen iguanasCerebral circulationVentricular morphologyRadiopaque contrastArterial circulationCorrosionArterial branchesVentricular systemRadiography studiesMorphologyArterial segmentsArterial structureAnatomic informationTomography imagingBrainArterial capillariesArterial network
2020
Small airways pathology in idiopathic pulmonary fibrosis: a retrospective cohort study
Verleden SE, Tanabe N, McDonough JE, Vasilescu DM, Xu F, Wuyts WA, Piloni D, De Sadeleer L, Willems S, Mai C, Hostens J, Cooper JD, Verbeken EK, Verschakelen J, Galban CJ, Van Raemdonck DE, Colby TV, Decramer M, Verleden GM, Kaminski N, Hackett TL, Vanaudenaerde BM, Hogg JC. Small airways pathology in idiopathic pulmonary fibrosis: a retrospective cohort study. The Lancet Respiratory Medicine 2020, 8: 573-584. PMID: 32061334, PMCID: PMC7292784, DOI: 10.1016/s2213-2600(19)30356-x.Peer-Reviewed Original ResearchConceptsIdiopathic pulmonary fibrosisSevere idiopathic pulmonary fibrosisUnused donor lungsRetrospective cohort studyTerminal bronchiolesMultidetector CTCohort studyDonor lungsPulmonary fibrosisIPF tissueLung tissueMinimal fibrosisVideo-assisted thoracic surgical biopsyDiagnosis of IPFAshcroft fibrosis scoreMultidisciplinary consensus committeeStructural lung injuryInflammatory immune cellsExpiratory flow rateLow lung volumesPotential therapeutic targetMicro-CTLung transplantationVisible airwaysIPF group
2017
Selective deletion of the soluble Colony-Stimulating Factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice
Yao GQ, Troiano N, Simpson CA, Insogna KL. Selective deletion of the soluble Colony-Stimulating Factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice. Bone Research 2017, 5: 17022. PMID: 29152381, PMCID: PMC5684603, DOI: 10.1038/boneres.2017.22.Peer-Reviewed Original ResearchBone mineral densityEstrogen-deficiency bone lossBone lossO miceTotal bone mineral densityWild-type female miceDual-energy X-ray absorptiometryX-ray absorptiometrySham-OVXReverse transcription-PCRFemale miceMineral densityWT controlsOVXSelective deletionMiceTranscription-PCRSignificant differencesCSF1Bone tissueMicro-CTSkeletal tissuesTissueNon-redundant functionsAnimals
2015
Multimodality Imaging of Ethiodized Oil-loaded Radiopaque Microspheres during Transarterial Embolization of Rabbits with VX2 Liver Tumors.
Tacher V, Duran R, Lin M, Sohn JH, Sharma KV, Wang Z, Chapiro J, Gacchina Johnson C, Bhagat N, Dreher MR, Schäfer D, Woods DL, Lewis AL, Tang Y, Grass M, Wood BJ, Geschwind JF. Multimodality Imaging of Ethiodized Oil-loaded Radiopaque Microspheres during Transarterial Embolization of Rabbits with VX2 Liver Tumors. Radiology 2015, 279: 741-53. PMID: 26678453, PMCID: PMC4886703, DOI: 10.1148/radiol.2015141624.Peer-Reviewed Original ResearchConceptsTransarterial embolizationLiver tumor modelFeeding arteriesContrast materialMultidetector CTEmbolic agentTumor modelRabbit VX2 liver tumor modelRadiopaque microspheresVX2 tumor-bearing rabbitsCone-beam CTContrast material washoutRabbit liver tumor modelVX2 liver tumor modelTumor feeding arteriesVX2 rabbit liver tumor modelMicro-CTHistologic examinationInstitutional Animal CareTumor enhancementKruskal-Wallis testScale scoreHistologic analysisEmbolizationCone beam
2012
Trapezium Trabecular Morphology in Carpometacarpal Arthritis
Lee A, Williams A, Lee J, Cheng R, Lindsey D, Ladd A. Trapezium Trabecular Morphology in Carpometacarpal Arthritis. The Journal Of Hand Surgery 2012, 38: 309-315. PMID: 23267754, PMCID: PMC3932241, DOI: 10.1016/j.jhsa.2012.10.038.Peer-Reviewed Original ResearchConceptsTrabecular morphologyBone volume fractionTrabecular numberMicro-CTNormal specimensBone morphology parametersTrabecular bone volumeThumb carpometacarpal osteoarthritisBone volume ratioMicro-CT analysisNo significant differencePredominant trabecular patternArthritis developmentBone volumeQuadrant measurementsTrabecular patternBony remodelingCarpometacarpal osteoarthritisTrabecular thicknessSignificant differenceTrabecularPathological alterationsBoneQuadrantVolar-ulnar
2011
Fine balance between HIF1 and HIF2 in smooth muscle is crucial for normal development and survival
Lei L, Liu D, Jiang W, Huang Y, Giordano F. Fine balance between HIF1 and HIF2 in smooth muscle is crucial for normal development and survival. The FASEB Journal 2011, 25: 616.10-616.10. DOI: 10.1096/fasebj.25.1_supplement.616.10.Peer-Reviewed Original ResearchSmooth muscle cellsVon Hippel-LindauSmooth muscleDied of heart failureDeletion of von Hippel-LindauDouble knockoutVascular smooth muscle cellsMicro-CT angiographyNormal developmentEmbryonic lethalityApparent etiologyMidline defectsFetal developmentVascular reactivityEctopia cordisE14.5-15.5Heart failureMuscle cellsVascular spasmIntramyocardial hematomaVascular perfusionMiceGastroschisisVascular segmentsMicro-CTBone Regeneration of Tibial Segmental Defect Using Isotropic-Pore Structures Hydroxyapatite/Alumina Bi-Layered Scaffold: In Vivo Pilot Study
Son J, Kim JM, Han M, Choi S, Lee F, Oh D. Bone Regeneration of Tibial Segmental Defect Using Isotropic-Pore Structures Hydroxyapatite/Alumina Bi-Layered Scaffold: In Vivo Pilot Study. Journal Of Long-Term Effects Of Medical Implants 2011, 21: 159-167. PMID: 22043974, DOI: 10.1615/jlongtermeffmedimplants.v21.i2.60.Peer-Reviewed Original ResearchConceptsBi-layer scaffoldLayered scaffoldsBi-layered scaffoldIsotropic pore structureLarge segmental defectsEnergy dispersive spectroscopyBone regenerationAlumina scaffoldsCoating techniqueDispersive spectroscopyPore sizeSegmental defectsTibia modelBone substituteTibial segmental defectInner layerAluminaElectron microscopyOuter layerBone defectsMicro-CTNew bone formationLayerScaffoldsPorosity
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