Apolipoproteins L1 and L3 control mitochondrial membrane dynamics
Lecordier L, Heo P, Graversen J, Hennig D, Skytthe M, d’Elzius A, Pincet F, Pérez-Morga D, Pays E. Apolipoproteins L1 and L3 control mitochondrial membrane dynamics. Cell Reports 2023, 42: 113528. PMID: 38041817, PMCID: PMC10765320, DOI: 10.1016/j.celrep.2023.113528.Peer-Reviewed Original ResearchConceptsVesicle-associated membrane protein 8Mitochondrial membrane dynamicsPI4KBMembrane dynamicsPI4KB activityMembrane protein 8Mitochondrial reactive oxygen speciesNeuronal calcium sensor-1Apolipoprotein L1C-terminal truncationsEndolysosomal membranesFission factorCalneuron-1Mitochondria fissionProhibitin 2Reactive oxygen speciesMitophagy fluxProtein 8APOL3KbOxygen speciesGolgiKB activityAPOL1MitophagyWCN23-0470 BAC-transgenic mice show a novel T-cell intrinsic role for FSGS-associated APOL1 risk-variants in T-cell activation
Pell J, Reghuvaran A, Nagata S, Banu K, He J, Craft J, Shi H, Chernova I, Ishibe S, Menon M. WCN23-0470 BAC-transgenic mice show a novel T-cell intrinsic role for FSGS-associated APOL1 risk-variants in T-cell activation. Kidney International Reports 2023, 8: s392-s393. DOI: 10.1016/j.ekir.2023.02.882.Peer-Reviewed Original Research
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