2024
Gene Copy Number Alterations Identify Subsets of Mycosis Fungoides/Sézary Syndrome Patients with Worse Survival Outcomes
Kiwan A, Kewan T, Xu M, Siddon A, Girardi M, Sethi T, Foss F. Gene Copy Number Alterations Identify Subsets of Mycosis Fungoides/Sézary Syndrome Patients with Worse Survival Outcomes. Blood 2024, 144: 4440-4440. DOI: 10.1182/blood-2024-205144.Peer-Reviewed Original ResearchGene copy number alterationsAssociated with poor OSAbsolute lymphocyte countFluorescence in situ hybridization panelAssociated with worse OSCirculating Tumor CellsFluorescence in situ hybridizationOverall survivalCopy number alterationsT cell receptorPoor OSSurvival outcomesTumor cellsMedian OSCox proportional hazardsBlood involvementATM deletionArid1a deletionT cellsElevated absolute lymphocyte countMedian absolute lymphocyte countAssociated with better OSMedian age of patientsMultivariate CPH modelZEB1 deletionPatterns of CNS Failures in Relapse/Refractory Large B-Cell Lymphoma (LBCL) Patients with Secondary CNS Disease Following Chimeric Antigen Receptor T-Cell (CAR T) Therapy
Nakashima J, Khatri V, Cruz-Chamorro R, Zhou J, Patra P, Gaballa S, Khimani F, Mirza S, Shah B, Saeed H, Chavez J, Locke F, Nishihori T, Liu H, Dong N, Lazaryan A, Robinson T, Freeman C, Jain M, Figura N. Patterns of CNS Failures in Relapse/Refractory Large B-Cell Lymphoma (LBCL) Patients with Secondary CNS Disease Following Chimeric Antigen Receptor T-Cell (CAR T) Therapy. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: e646-e647. DOI: 10.1016/j.ijrobp.2024.07.1421.Peer-Reviewed Original ResearchLarge B-cell lymphomaSecondary CNS lymphomaB-cell lymphomaCNS failureCNS recurrenceCNS diseaseCNS lymphomaCAR-TOverall survivalBridging therapyCNS diagnosisRelapsed/refractory large B-cell lymphomaChimeric antigen receptor T cellsCAR-T cell trialsPattern of failure analysisCAR-T cell therapyMedian age of patientsClinical outcomes of patientsCNS-only progressionSystemic disease recurrenceT-cell therapyCAR-T therapyCytokine-release syndromePatterns of recurrenceKaplan-Meier methodAssociation between thymectomy and incidence of renal cell carcinoma (RCC).
Barragan-Carrillo R, Ebrahimi H, Chawla N, Salgia N, Castro D, Chehrazi-Raffle A, Dizman N, Hsu J, Meza L, Zengin Z, LeVee A, Tripathi A, Dorff T, Bergerot C, Bergerot P, Eilber K, Dallas K, Pal S. Association between thymectomy and incidence of renal cell carcinoma (RCC). Journal Of Clinical Oncology 2024, 42: 371-371. DOI: 10.1200/jco.2024.42.4_suppl.371.Peer-Reviewed Original ResearchRenal cell carcinomaIncidence of nephrectomyIncidence of renal cell carcinomaMedian age of patientsFrequency of nephrectomyAge of patientsT cell productionProportion of patientsRate of nephrectomyFisher's exact testGeneral populationAge-matched populationICD-9/10 codesPopulation-based cohortPopulation-based studyImmunogenic cancerPrior thymectomyChi-square testCell carcinomaMedian ageSurgical interventionNephrectomyThymectomyExact testOSHPD database
2015
Immunohistochemistry – Microarray Analysis of Patients with Peritoneal Metastases of Appendiceal or Colorectal Origin
Green D, Jayakrishnan T, Hwang M, Pappas S, Gamblin T, Turaga K. Immunohistochemistry – Microarray Analysis of Patients with Peritoneal Metastases of Appendiceal or Colorectal Origin. Frontiers In Surgery 2015, 1: 50. PMID: 25593974, PMCID: PMC4286965, DOI: 10.3389/fsurg.2014.00050.Peer-Reviewed Original ResearchPeritoneal carcinomatosis indexPeritoneal metastasisColorectal PMColorectal primaryBRAF mutationsPeritoneal carcinomatosis index scoreMedian age of patientsAnalysis of pathological specimensAssociated with previous useAppendiceal primary tumorsAge of patientsAnalysis of patientsManagement of patientsCharacteristics of patientsSample of patientsAppendiceal PMSufficient tumorColorectal originPrimary tumorConsecutive patientsApparent high incidenceMedian ageKRAS mutationsPathological specimensBiomarker expression
2014
Molecular profiling in gastric cancer: Examining potential targets for chemotherapy
Miura J, Johnston F, Thomas J, George B, Eastwood D, Tsai S, Christians K, Turaga K, Gamblin T. Molecular profiling in gastric cancer: Examining potential targets for chemotherapy. Journal Of Surgical Oncology 2014, 110: 302-306. PMID: 24844210, DOI: 10.1002/jso.23639.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedAntigens, NeoplasmAntineoplastic Combined Chemotherapy ProtocolsATP Binding Cassette Transporter, Subfamily B, Member 1BiomarkersCisplatinDNA Topoisomerases, Type IDNA Topoisomerases, Type IIDNA-Binding ProteinsDrug Resistance, NeoplasmEndonucleasesEpirubicinFemaleFluorouracilHumansImmunohistochemistryMaleMiddle AgedNeoplasm ProteinsPoly-ADP-Ribose Binding ProteinsStomach NeoplasmsThymidylate SynthaseConceptsGastric adenocarcinomaMolecular profilingMedian age of patientsManagement of GC patientsOperable gastric adenocarcinomaAge of patientsMolecular profiling of GCProspective Controlled StudyGC specimensCytotoxic regimensMedian ageNCCN guidelinesTOPO1 expressionGastric cancerNegative TSTherapeutic approachesGC patientsPatientsImmunohistochemistrySimultaneous expression analysisERCC1TherapyGene expression levelsPotential targetExpression levelsMolecular profiling in gastric cancer: Examining potential targets for chemotherapy.
Miura J, Jayakrishnan T, Eastwood D, Johnston F, Tsai S, Christians K, Turaga K, Gamblin T. Molecular profiling in gastric cancer: Examining potential targets for chemotherapy. Journal Of Clinical Oncology 2014, 32: 131-131. DOI: 10.1200/jco.2014.32.3_suppl.131.Peer-Reviewed Original ResearchGastric adenocarcinomaMolecular profilingMedian age of patientsManagement of GC patientsOperable gastric adenocarcinomaAge of patientsProspective Controlled StudyGC specimensMedian ageNCCN guidelinesPerioperative epirubicinTS expressionGastric cancerNegative TSTherapeutic approachesGC patientsPatientsRoutine managementERCC1TherapyBiomarker profilesEvaluate expressionTOP2ABiomarker analysisBiomarkers
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