2023
Impact of childhood maltreatment on adult resilience
Li C, Lv G, Liu B, Ju Y, Wang M, Dong Q, Sun J, Lu X, Zhang L, Wan P, Guo H, Zhao F, Liao M, Zhang Y, Li L, Liu J. Impact of childhood maltreatment on adult resilience. BMC Psychiatry 2023, 23: 637. PMID: 37648984, PMCID: PMC10470179, DOI: 10.1186/s12888-023-05124-w.Peer-Reviewed Original ResearchConceptsMajor depressive disorder groupsMajor depressive disorderChildhood Trauma QuestionnaireChildhood maltreatmentEmotional neglectAdult resiliencePhysical neglectEmotional abuseHealthy controlsChildhood Trauma Questionnaire total scoreHC groupImpact of childhood maltreatmentCD-RISCSevere childhood maltreatmentAssociated with poor health outcomesConnor-Davidson Resilience ScaleScores of CD-RISCDepressive disorderPoor health outcomesTrauma QuestionnairePoor mental healthPsychiatric hospitalOptimality scoreTraumatized peopleFactor scores
2019
Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder
Pizzagalli D, Berretta S, Wooten D, Goer F, Pilobello K, Kumar P, Murray L, Beltzer M, Boyer-Boiteau A, Alpert N, Fakhri G, Mechawar N, Vitaliano G, Turecki G, Normandin M. Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder. JAMA Psychiatry 2019, 76: 854-861. PMID: 31042280, PMCID: PMC6495358, DOI: 10.1001/jamapsychiatry.2019.0801.Peer-Reviewed Original ResearchConceptsMajor depressive disorderDA transporter availabilityVentral tegmental areaDA transporterDAT availabilityTegmental areaDepressive disorderDA signalingPositron emission tomographyDAT expressionMcLean HospitalHealthy controlsMajor depressive disorder groupsNumbers of depressive episodesStriatal dopamine transporter bindingDA transporter levelsLevels of DAT expressionStriatal DAT expressionStriatal DAT availabilityDA transporter densityDAT binding potentialDopamine transporter bindingOlder healthy controlsMesolimbic pathwayDA clearance
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