2013
Substance abuse and the HIV situation in Malaysia
Singh D, Chawarski MC, Schottenfeld R, Vicknasingam B. Substance abuse and the HIV situation in Malaysia. Journal Of Food And Drug Analysis 2013, 21: s46-s51. PMID: 25278737, PMCID: PMC4179250, DOI: 10.1016/j.jfda.2013.09.033.Peer-Reviewed Original ResearchInjection drug usersNeedle-syringe exchange programsDrug usersAmphetamine-type stimulantsAntiretroviral treatmentHIV infectionAgonist maintenance treatmentCumulative HIV casesInjection drug useMethadone maintenance treatment centersSyringe exchange programsSignificant increaseMaintenance treatment centersHarm reduction approachHeroin seizuresHIV casesHIV prevalenceMaintenance treatmentActive patientsHIV situationEffective treatmentOpiate dependenceAbuse disordersMain drugsMedical treatment
2005
Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes
Fadili K, Messier N, Leprohon P, Roy G, Guimond C, Trudel N, Saravia NG, Papadopoulou B, Légaré D, Ouellette M. Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes. Antimicrobial Agents And Chemotherapy 2005, 49: 1988-1993. PMID: 15855523, PMCID: PMC1087671, DOI: 10.1128/aac.49.5.1988-1993.2005.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntimonyAntimony Sodium GluconateATP-Binding Cassette TransportersCell LineCysteineDNA, ProtozoanDrug ResistanceGlutathioneLeishmania infantumMembrane GlycoproteinsMicroscopy, ConfocalMonocytesOligonucleotide Array Sequence AnalysisProtozoan ProteinsRibonucleoproteinsSaccharomyces cerevisiae ProteinsSpermidineTransfectionConceptsABC transporter MRPAAntimony resistanceSodium stibogluconate (SSG) resistanceTreatment of infectionsMRPA geneSodium stibogluconateAntimonial compoundsMain drugsAmastigote parasitesPutative alterationsIntracellular amastigotesLevel of expressionProtozoan parasite LeishmaniaIntracellular parasitesAxenic amastigotesButhionine sulfoximineLevels of cysteineAmastigote stageDNA microarraysS-adenosylhomocysteine hydrolaseParasite LeishmaniaPotassium antimonyl tartrateAmastigotesLeishmaniaGenes
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