2024
Sorting of secretory proteins at the trans-Golgi network by human TGN46
Lujan P, Garcia-Cabau C, Wakana Y, Lillo J, Rodilla-Ramírez C, Sugiura H, Malhotra V, Salvatella X, Garcia-Parajo M, Campelo F. Sorting of secretory proteins at the trans-Golgi network by human TGN46. ELife 2024, 12: rp91708. PMID: 38466628, PMCID: PMC10928510, DOI: 10.7554/elife.91708.Peer-Reviewed Original ResearchConceptsSecretory proteinsSorting of secretory proteinsCargo-sorting functionsTrans-Golgi networkNascent carriersCargo sortingLumenal domainMutagenesis approachTGN46Quantitative fluorescence microscopyCellular functionsMolecular playersTGNTransport carriersProteinFluorescence microscopyMembrane carrierSorting functionFundamental processesSortingCargoMutagenesisExportPAUFReceptorsSorting of secretory proteins at the trans-Golgi network by human TGN46
Lujan P, Garcia-Cabau C, Wakana Y, Vera Lillo J, Rodilla-Ramírez C, Sugiura H, Malhotra V, Salvatella X, Garcia-Parajo M, Campelo F. Sorting of secretory proteins at the trans-Golgi network by human TGN46. ELife 2024, 12 DOI: 10.7554/elife.91708.3.Peer-Reviewed Original ResearchTrans Golgi networkSecretory proteinsSorting of secretory proteinsCargo-sorting functionsTrans-Golgi networkNascent carriersCargo sortingGolgi networkLumenal domainMutagenesis approachTGN46Quantitative fluorescence microscopyCellular functionsMolecular playersTransport carriersProteinFluorescence microscopyMembrane carrierSorting functionFundamental processesSortingCargoMutagenesisExportPAUF
2021
Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome
Chandra S, Mannino PJ, Thaller DJ, Ader NR, King MC, Melia TJ, Lusk CP. Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome. Journal Of Cell Biology 2021, 220: e202103030. PMID: 34714326, PMCID: PMC8575018, DOI: 10.1083/jcb.202103030.Peer-Reviewed Original ResearchMeSH KeywordsAutophagosomesAutophagyAutophagy-Related ProteinsCytoplasmic VesiclesGreen Fluorescent ProteinsNuclear EnvelopeProtein DomainsReceptors, Cytoplasmic and NuclearSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsStructure-Activity RelationshipTime FactorsVacuolesVesicular Transport ProteinsConceptsInner nuclear membraneNuclear envelope lumenOuter nuclear membraneNuclear membraneSplit-GFP reporterNuclear envelope localizationINM proteinsAutophagy apparatusEnvelope localizationLumenal vesiclesLumenal domainCargo adaptorsAtg39Sequence elementsCorrelative lightVesiclesAutophagosomesMembraneNucleophagyAdaptorReporterProteinOverexpressionMotif
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