Higher BMI is associated with smaller regional brain volume in older adults with type 2 diabetes
West R, Livny A, Ravona-Springer R, Bendlin B, Heymann A, Leroith D, Liu X, Lin H, Hochner H, Friedlander Y, Ganmore I, Tirosh A, Schnaider Beeri M. Higher BMI is associated with smaller regional brain volume in older adults with type 2 diabetes. Diabetologia 2020, 63: 2446-2451. PMID: 32862254, PMCID: PMC7530092, DOI: 10.1007/s00125-020-05264-8.Peer-Reviewed Original ResearchConceptsAssociation of adiposityInferior frontal gyrusType 2 diabetesRegional brain volumesOlder adultsFrontal gyrusSample of older individualsTrajectories of BMICognitive Decline studyLong-term trajectoriesAssociation of BMIBMI trajectory groupsTrajectory of obesityLong-term adiposityBrain volumeAssociated with smaller regional brain volumesInferior frontal gyrus volumeRelevant to cognitive functionTotal gray matter volumeDementia riskAssociated with smaller volumesMiddle frontal gyrusMiddle temporal gyrusSuperior frontal gyrusGray matter volume
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