1994
The Effect of Nasal CPAP on Nocturnal Reflux in Patients With Aperistaltic Esophagus
Shoenut J, Kerr P, Micflikier A, Yamashiro Y, Kryger M. The Effect of Nasal CPAP on Nocturnal Reflux in Patients With Aperistaltic Esophagus. CHEST Journal 1994, 106: 738-741. PMID: 8082351, DOI: 10.1378/chest.106.3.738.Peer-Reviewed Original ResearchConceptsNocturnal refluxNasal CPAPAperistaltic esophagusLES pressureReflux eventsNasal continuous positive airway pressureContinuous positive airway pressureLower esophageal sphincter pressurePositive airway pressureEsophageal sphincter pressureGroup of patientsScleroderma esophagusScleroderma groupAirway pressureSphincter pressureSleep apneaPercentage of timeCPAPPatientsSecond nightRefluxEsophagusFirst nightAchalasiaGroup
1993
Effects of intrasphincteric botulinum toxin on the lower esophageal sphincter in piglets
Pasricha P, Ravich W, Kalloo A. Effects of intrasphincteric botulinum toxin on the lower esophageal sphincter in piglets. Gastroenterology 1993, 105: 1045-1049. PMID: 8405847, DOI: 10.1016/0016-5085(93)90947-b.Peer-Reviewed Original ResearchConceptsLES pressureLower esophageal sphincter pressureIntrasphincteric botulinum toxinEsophageal sphincter pressureLower esophageal sphincterRelease of acetylcholineGastrointestinal smooth muscleNormal saline injectionEvidence of toxicityBaseline lower esophageal sphincter pressureBoTx injectionNoncholinergic pathwaysAnticholinergic effectsSphincter pressureLES toneEsophageal sphincterGastrointestinal sphinctersBotulinum toxinNormal salineSaline injectionNerve terminalsParadoxical responseSmooth muscleBoTxSkeletal muscle
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