2024
Vaccine development: obligate intracellular bacteria new tools, old pathogens: the current state of vaccines against obligate intracellular bacteria
van Schaik E, Fratzke A, Gregory A, Dumaine J, Samuel J. Vaccine development: obligate intracellular bacteria new tools, old pathogens: the current state of vaccines against obligate intracellular bacteria. Frontiers In Cellular And Infection Microbiology 2024, 14: 1282183. PMID: 38567021, PMCID: PMC10985213, DOI: 10.3389/fcimb.2024.1282183.Peer-Reviewed Original ResearchProtective immunityCD8+ T cell responsesEffective antibody-based vaccineT cell memory responsesImmune responseIntracellular bacteriaT cell responsesAntibody-based vaccinesObligate intracellular bacteriaNovel delivery platformCytotoxic CD8Chlamydia trachomatisMemory responsesHumoral responseSuccessful vaccinesAnimal modelsAntibody responseAntigen discoveryEfficacious vaccinesVaccine developmentEffective vaccineSARS-CoV-2CD8VaccineSARS-CoV-2 pandemic
2013
Follicular T‐helper cells: controlled localization and cellular interactions
Qi H, Chen X, Chu C, Lu P, Xu H, Yan J. Follicular T‐helper cells: controlled localization and cellular interactions. Immunology And Cell Biology 2013, 92: 28-33. PMID: 24145857, DOI: 10.1038/icb.2013.59.Peer-Reviewed Original ResearchConceptsB cell responsesGerminal centersTfh cellsEffective antibody-based vaccineFollicular T helper cellsDependent B cell responsesIsotype-switched antibodiesAntibody-based vaccinesCD4 T cellsT helper cellsHumoral autoimmunityHumoral protectionT cellsTranscriptional repressor Bcl-6Surface phenotypeSuch antibodiesBCL-6Microbial infectionsGC reactionAntibodiesCellsCellular interactionsCurrent understandingHigh levelsAutoimmunityTissue‐resident memory T cells
Shin H, Iwasaki A. Tissue‐resident memory T cells. Immunological Reviews 2013, 255: 165-181. PMID: 23947354, PMCID: PMC3748618, DOI: 10.1111/imr.12087.Peer-Reviewed Original ResearchConceptsMemory T cellsHuman immunodeficiency virusHerpes simplex virusGenital tractT cellsPeripheral tissuesImmune systemTissue-resident memory T cellsMemory T cell migrationTissue-resident memory cellsT cell-based vaccinesMemory T cell populationsMemory T cell subsetsAntibody-based vaccinesT cell recruitmentT cell subsetsNew vaccination strategiesT cell populationsSecondary lymphoid organsNon-lymphoid tissuesPortal of entryT cell migrationAdaptive immune systemTRM cellsEffector memory
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