Regulation of CD1 Antigen-presenting Complex Stability*
Odyniec A, Barral D, Garg S, Tatituri R, Besra G, Brenner M. Regulation of CD1 Antigen-presenting Complex Stability*. Journal Of Biological Chemistry 2010, 285: 11937-11947. PMID: 20133943, PMCID: PMC2852931, DOI: 10.1074/jbc.m109.077933.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigen PresentationAntigens, CD1beta 2-MicroglobulinCell LineCell MembraneEndosomesHeLa CellsHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHumansHydrogen-Ion ConcentrationLysosomesMiceMultiprotein ComplexesProtein IsoformsProtein StabilityRecombinant ProteinsTransfectionConceptsCD1 heavy chainsCell surfaceHeavy chainEndosomal pHQuality control mechanismsCD1 proteinsCell surface pHCD1 isoformsLipid antigensAcidic endosomal pHAntigen-loading complexesPH optimaAcidic pHIntracellular compartmentsMildly acidic pHLipid exchangeAntigen bindingNeutral pHTraffickingPeptide antigensCellsBindingCD1LipidBeta(2)-microglobulin
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