PLA2R antibodies, glomerular PLA2R deposits and variations in PLA2R1 and HLA-DQA1 genes in primary membranous nephropathy in South Asians
Ramachandran R, Kumar V, Kumar A, Yadav A, Nada R, Kumar H, Kumar V, Rathi M, Kohli H, Gupta K, Sakhuja V, Jha V. PLA2R antibodies, glomerular PLA2R deposits and variations in PLA2R1 and HLA-DQA1 genes in primary membranous nephropathy in South Asians. Nephrology Dialysis Transplantation 2015, 31: 1486-1493. PMID: 26673907, DOI: 10.1093/ndt/gfv399.Peer-Reviewed Original ResearchConceptsAnti-PLA2R titerHLA-DQA1 geneAnti-PLA2RHLA-DQA1Glomerular stainingAssociated with PMNAntibodies to m-type phospholipase A2 receptorNephrotic stateM-type phospholipase A2 receptorRemission of nephrotic syndromeAnti-PLA2R levelsAnti-PLA2R positivityGlomerular PLA2R depositionGlomerular PLA2R stainingSerum anti-PLA2RMonths of therapyPhospholipase A2 receptorResponse to therapyHigh-risk genotypesResponse to treatmentFresh frozen tissuePLA2R stainingPMN patientsPLA2R antibodyA2 receptorsAntibodies to m‐type phospholipase A2 receptor in children with idiopathic membranous nephropathy
Kumar V, Ramachandran R, Kumar A, Nada R, Suri D, Gupta A, Kohli H, Gupta K, Jha V. Antibodies to m‐type phospholipase A2 receptor in children with idiopathic membranous nephropathy. Nephrology 2015, 20: 572-575. PMID: 26194981, DOI: 10.1111/nep.12478.Peer-Reviewed Original ResearchConceptsIdiopathic membranous nephropathyAntibodies to m-type phospholipase A2 receptorM-type phospholipase A2 receptorPhospholipase A2 receptorAnti-PLA2RA2 receptorsNephrotic syndromeMembranous nephropathyAnti-PLA2R levelsAnti-PLA2R titerAdult nephrotic syndromeCause of adult nephrotic syndromePLA2R stainingPLA2R antigenPLA2RGlomerular depositionAntibodiesNephropathyReceptors
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