2021
Serotonin as a Mitogen in the Gastrointestinal Tract: Revisiting a Familiar Molecule in a New Role
Shah PA, Park CJ, Shaughnessy MP, Cowles RA. Serotonin as a Mitogen in the Gastrointestinal Tract: Revisiting a Familiar Molecule in a New Role. Cellular And Molecular Gastroenterology And Hepatology 2021, 12: 1093-1104. PMID: 34022423, PMCID: PMC8350061, DOI: 10.1016/j.jcmgh.2021.05.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEnteric nervous systemSerotonin receptorsGI tractPotentiation of serotoninInflammatory bowel diseaseVascular smooth muscleIntestinal epithelial proliferationIntestinal crypt cellsBody's serotoninMalabsorptive conditionsIntestinal injuryEnteric neuronsIntestinal motilityBowel diseaseIntestinal inflammationEnterochromaffin cellsGI diseaseSerotonergic neuronsMuscarinic receptorsCholinergic signalingSerotonin synthesisGastrointestinal systemGastrointestinal tractIntestinal mucosaSmooth muscle
2015
Geometry of the Gene Expression Space of Individual Cells
Korem Y, Szekely P, Hart Y, Sheftel H, Hausser J, Mayo A, Rothenberg M, Kalisky T, Alon U. Geometry of the Gene Expression Space of Individual Cells. PLOS Computational Biology 2015, 11: e1004224. PMID: 26161936, PMCID: PMC4498931, DOI: 10.1371/journal.pcbi.1004224.Peer-Reviewed Original ResearchConceptsGene expression spaceExpression spaceCell typesConcept of cell typesGene expressionGene expression of single cellsHigh-dimensional gene expression spaceEvolutionary trade-offIntestinal progenitor cellsSingle-cell dataSingle-cell datasetsSingle-cell technologiesSingle cellsMultiple tasksExpression statesIntestinal crypt cellsPathogen sensingMouse tissuesGenesExpression profilesTask
1996
Expression of Tyrosine Kinases in the Mouse Small Intestine
Tyner A, Vasioukhin V, Serfas M, Siyanova E, Llor X. Expression of Tyrosine Kinases in the Mouse Small Intestine. NATO ASI Series 1996, 309-318. DOI: 10.1007/978-3-642-61180-3_28.Peer-Reviewed Original ResearchTyrosine kinaseIntestinal crypt cellsMouse small intestinePolymerase chain reaction techniqueMammalian intestinal epitheliumChain reaction techniqueGastrointestinal tractSmall intestineIntestinal epitheliumCrypt cellsEpitheliumAlimentary canalContinuous proliferationHuman tyrosine kinasesSignal transduction pathwaysCell differentiation
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