Imaging Demyelinated Axons After Spinal Cord Injuries with PET Tracer [18F]3F4AP
Ramos-Torres K, Conti S, Zhou Y, Tiss A, Caravagna C, Takahashi K, He M, Wilks M, Eckl S, Sun Y, Biundo J, Gong K, He Z, Linnman C, Brugarolas P. Imaging Demyelinated Axons After Spinal Cord Injuries with PET Tracer [18F]3F4AP. Journal Of Nuclear Medicine 2025, 66: jnumed.124.268242. PMID: 39819685, PMCID: PMC11800733, DOI: 10.2967/jnumed.124.268242.Peer-Reviewed Original ResearchSpinal cord injuryDemyelinated axonsIncomplete injuryPostmortem spinal cord tissueSpinal cord blood flowSpinal cord injury ratsResponse to therapyCord injuryCord blood flowManagement of spinal cord injurySpinal cord tissuePET imaging resultsSensitive to injuryInjured segmentContusion injuryAxonal lossCord tissueDemyelinating changesAnimal modelsDemyelinationPET imagingBlood flowPET tracersWorsening disabilityTracer binding
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