1998
Immunohistochemical localization of inducible nitric oxide synthase on human fetal amnion in intra-amniotic infection
Hsu C, Meaddough E, Lu L, Chelouche A, Liang R, Copel J, Parkash V. Immunohistochemical localization of inducible nitric oxide synthase on human fetal amnion in intra-amniotic infection. American Journal Of Obstetrics And Gynecology 1998, 179: 1271-1274. PMID: 9822514, DOI: 10.1016/s0002-9378(98)70145-0.Peer-Reviewed Original ResearchConceptsInducible nitric oxide synthaseIntra-amniotic infectionNitric oxide synthaseFetal amniotic membranesOxide synthaseFetal amnionNitric oxideAmniotic membranePositive amniotic fluid culturePlacental pathologic featuresAmniotic fluid levelsNitric oxide metabolitesAnti-inducible nitric oxide synthaseAmniotic fluid cultureNormal rabbit serumOvarian carcinoma cellsHuman inducible nitric oxide synthaseInfectious productsPathologic featuresOxide metabolitesFluid culturePositive immunostainingRabbit polyclonal antibodyImmunohistochemical localizationFluid levels
1997
Bacterial infection induces nitric oxide synthase in human neutrophils.
Wheeler MA, Smith SD, García-Cardeña G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. Journal Of Clinical Investigation 1997, 99: 110-116. PMID: 9011564, PMCID: PMC507774, DOI: 10.1172/jci119121.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnti-Bacterial AgentsArginineBacterial InfectionsBlotting, WesternCanavanineCell MembraneCitrullineFemaleGuanidinesHumansImmunohistochemistryIsoenzymesLeukocyte Common AntigensMaleMiddle AgedNeutrophilsNG-Nitroarginine Methyl EsterNitric Oxide SynthaseNitroarginineomega-N-MethylarginineOrnithinePolymerase Chain ReactionRNA, MessengerSulfonamidesThioureaTrifluoperazineUrinary Tract InfectionsConceptsInducible nitric oxide synthaseUrinary tract infectionNitric oxide synthaseNitric oxide synthase activityTract infectionsOxide synthase activityOxide synthaseInducible nitric oxide synthase activityNitric oxide synthase proteinNitric oxide synthase isoformsInduces nitric oxide synthaseMajor nitric oxide synthase isoformHuman inflammatory cellsHuman inducible nitric oxide synthaseExtended elevationInflammatory cellsProinflammatory functionsAntibiotic treatmentInflammatory processSynthase activityImmunocytochemical evidenceHuman neutrophilsInfectionCalcium independentSynthase isoforms
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