2025
Reclassification of pineal tumor as high-grade astrocytoma with piloid features through methylation profiling: illustrative case
Dincer A, Kim M, Hüseyinoglu Z, Chavez M, McGuone D, Moliterno J. Reclassification of pineal tumor as high-grade astrocytoma with piloid features through methylation profiling: illustrative case. Journal Of Neurosurgery Case Lessons 2025, 9: case24778. PMID: 40324324, PMCID: PMC12051993, DOI: 10.3171/case24778.Peer-Reviewed Original ResearchHigh-grade astrocytomasPiloid featuresHigh-grade neuroepithelial tumorCNS tumor classificationGross-total resectionHigh-grade pathologyEndoscopic third ventriculostomyRight-sided weaknessMethylation profilesClinically relevant changesNeuroepithelial tumorsSuboccipital craniectomyTumor sizePineal tumorsPineal regionThird ventriculostomyTumor typesClinical trialsGlioma subtypesBiopsy samplesDNA methylation profilesTumorTargeted therapeuticsHistological appearanceInterval increase
2010
An Implantable Vascularized Protein Gel Construct That Supports Human Fetal Hepatoblast Survival and Infection by Hepatitis C Virus in Mice
Harding MJ, Lepus CM, Gibson TF, Shepherd BR, Gerber SA, Graham M, Paturzo FX, Rahner C, Madri JA, Bothwell AL, Lindenbach BD, Pober JS. An Implantable Vascularized Protein Gel Construct That Supports Human Fetal Hepatoblast Survival and Infection by Hepatitis C Virus in Mice. PLOS ONE 2010, 5: e9987. PMID: 20376322, PMCID: PMC2848675, DOI: 10.1371/journal.pone.0009987.Peer-Reviewed Original ResearchConceptsHepatitis C virusHuman fetal hepatoblastsSmall animal modelsC virusAnimal modelsAccessible small animal modelsHuh-7.5 hepatoma cellsRobust small animal modelHuman hepatocyte engraftmentHuman albumin levelsBcl-2-transduced human umbilical vein endothelial cellsHuman umbilical vein endothelial cellsHepatocyte growth factorUmbilical vein endothelial cellsHCV infectionVein endothelial cellsAlbumin levelsHepatocyte engraftmentBeige miceImmunodeficient miceHistological appearanceImmunoelectron microscopic analysisMRNA expressionViral adsorptionHepatic epithelial cellsChanges in Gleason Scores for Prostate Cancer: What Should we Expect from a Measurement?
Ramos J, Uchio E, Aslan M, Concato J. Changes in Gleason Scores for Prostate Cancer: What Should we Expect from a Measurement? Journal Of Investigative Medicine 2010, 58: 625-628. DOI: 10.2310/jim.0b013e3181d4720c.Peer-Reviewed Original Research
2002
Deciduoid Mesothelioma: A Report of 5 Cases and Literature Review
Shia J, Erlandson R, Klimstra D. Deciduoid Mesothelioma: A Report of 5 Cases and Literature Review. Ultrastructural Pathology 2002, 26: 355-363. PMID: 12537760, DOI: 10.1080/0913120290104647.Peer-Reviewed Original ResearchConceptsCases of deciduoid mesotheliomaDeciduoid mesotheliomaPathological featuresHistory of asbestos exposureMonths to 5 yearsFollow-up timeFemale predominanceClinical findingsMorphologic spectrumMesotheliomaHistological appearanceSurvival timeAsbestos exposurePatientsYoung femalesAge rangePeritoneumDocumented historyMonthsUltrastructural basisIntermediate filamentsCytoplasmic intermediate filamentsReportsLiterature reportsPleura
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