2025
Gamma activation spread reflects disease activity in amyotrophic lateral sclerosis
Trubshaw M, Yoganathan K, Gohil C, Stagg C, Nobre A, Talbot K, Woolrich M, Thompson A, Turner M. Gamma activation spread reflects disease activity in amyotrophic lateral sclerosis. Clinical Neurophysiology 2025, 177: 2110823. PMID: 40610342, DOI: 10.1016/j.clinph.2025.2110823.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisDisease activityRegional spreadNeuronal oscillatory activityGamma activityHigher disease progression rateGamma frequency activityIsometric hand-grip exerciseNon-invasive measurementAmyotrophic lateral sclerosis groupHand-grip exerciseDisease progression rateLateral sclerosisMotor sub-scoresHealthy controlsMotor system dysfunctionSystem dysfunctionGrip strengthProgression rateFrequency activityOscillatory activityGrip exerciseSub-scoresSclerosisDisease
2022
Sympathetic Responses to Isometric Handgrip Exercise in Women following Preeclamptic Pregnancies
Orr H, Adler T, Leone C, Paidas M, Stachenfeld N, Usselman C. Sympathetic Responses to Isometric Handgrip Exercise in Women following Preeclamptic Pregnancies. The FASEB Journal 2022, 36 DOI: 10.1096/fasebj.2022.36.s1.r4218.Peer-Reviewed Original ResearchMuscle sympathetic nerve activityPost-exercise circulatory occlusionHand-grip exerciseElevated muscle sympathetic nerve activityHP womenMSNA responsesPreeclamptic pregnanciesBaseline muscle sympathetic nerve activityIsometric hand-grip exerciseSympathetic nerve activityIsometric handgrip exerciseTotal peripheral resistanceHG exerciseSympathetic dysregulationCardiovascular outcomesCirculatory occlusionHandgrip exerciseArterial pressureHealthy pregnancyNerve activityPE pregnanciesPeripheral resistanceGrip exercisePE womenCardiovascular disease
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